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SV2B antibody (AA 401-500) (Biotin)

SV2B Reactivity: Human, Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1390843
  • Target See all SV2B Antibodies
    SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))
    Binding Specificity
    • 14
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    AA 401-500
    Reactivity
    • 36
    • 23
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 30
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SV2B antibody is conjugated to Biotin
    Application
    • 30
    • 14
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SV2B
    Isotype
    IgG
    Top Product
    Discover our top product SV2B Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    SV2B (Synaptic Vesicle Glycoprotein 2B (SV2B))
    Alternative Name
    SV2B (SV2B Products)
    Synonyms
    SV2B antibody, A830038F04Rik antibody, AI850768 antibody, mKIAA0735 antibody, HsT19680 antibody, synaptic vesicle glycoprotein 2B antibody, synaptic vesicle glycoprotein 2 b antibody, synaptic vesicle glycoprotein 2b antibody, SV2B antibody, CpipJ_CPIJ009611 antibody, Sv2b antibody
    Background

    Synonyms: Synaptic vesicle protein 2B, SV2B_HUMAN.

    Background: In all vertebrates, SV2 proteins are abundant, hydrophobic, membrane glycoproteins that are expressed as two major isoforms, SV2A and SV2B, and one minor isoform, SV2C. SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, independent of transmitter type. SV2A is abundantly expressed in the subcortex, specifically in the synaptic vesicles of all presynaptic nerve terminals, and also in most neuroendocrine secretory granules. SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex. SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates. SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation.

    Gene ID
    9899
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