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ABLIM1 antibody (AA 681-778) (Alexa Fluor 555)

ABLIM1 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1391339
  • Target See all ABLIM1 Antibodies
    ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
    Binding Specificity
    • 14
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 681-778
    Reactivity
    • 41
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 37
    • 4
    Rabbit
    Clonality
    • 40
    • 1
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ABLIM1 antibody is conjugated to Alexa Fluor 555
    Application
    • 27
    • 13
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ABLIM1
    Isotype
    IgG
    Top Product
    Discover our top product ABLIM1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ABLIM1 (Actin Binding LIM Protein 1 (ABLIM1))
    Alternative Name
    ABLIM1 (ABLIM1 Products)
    Synonyms
    ABLIM1 antibody, 2210411C18Rik antibody, 2610209L21Rik antibody, 4833406P10Rik antibody, 9330196J19Rik antibody, AV079770 antibody, AW060987 antibody, AW215784 antibody, Limab1 antibody, abLIM-L antibody, abLIM-M antibody, abLIM-S antibody, mKIAA0059 antibody, ablim1 antibody, zgc:172321 antibody, RGD1565768 antibody, ABLIM antibody, LIMAB1 antibody, LIMATIN antibody, abLIM-1 antibody, si:dkeyp-84e12.1 antibody, zgc:112954 antibody, actin binding LIM protein 1 antibody, actin-binding LIM protein 1 antibody, actin binding LIM protein 1a antibody, actin binding LIM protein 1b antibody, ABLIM1 antibody, Ablim1 antibody, ablim1a antibody, ablim1b antibody
    Background

    Synonyms: ABLIM 1, ABLIM, abLIM-1, ABLIM-L, ABLIM-M, ABLIM-S, ABLIM1, ABLM1_HUMAN, Actin binding double zinc finger protein, Actin binding LIM protein 1, Actin binding LIM protein family member 1, Actin-binding double zinc finger protein, Actin-binding double zinc finger protein, Actin-binding LIM protein 1, Actin-binding LIM protein family member 1, DKFZp781D0148, FLJ14564, KIAA0059, LIM actin binding protein 1, LIMAB 1, LIMAB1, Limatin, RGD1565768, RP11-317F20.1.

    Background: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

    Gene ID
    3983
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