TWSG1 antibody (AA 151-223) (Alexa Fluor 555)

Catalog No. ABIN1392269

Product Details anti-TWSG1 Antibody (Alexa Fluor 555)

Target: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Binding Specificity: AA 151-223

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TWSG1 antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TWSG1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TWSG1

Target: TWSG1 (Twisted Gastrulation Homolog 1 (TWSG1))

Alternative Name: TWSG1 (TWSG1 Products)

Background:

Synonyms: PSEC0250, TSG, TSG1, twisted gastrulation homolog 1, Twisted gastrulation protein, TWSG1_HUMAN.

Background: Twisted Gastrulation Protein 1(TWSG1) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins thereby preventing BMPs from binding to their receptors. It can act either as a BMP4 agonist or antagonist (depending on the specific biochemical environment) by binding to the BMP4/Chordin complex.