Sorbs2 antibody (AA 401-500) (Alexa Fluor 488)

Catalog No. ABIN1396983

Product Details anti-Sorbs2 Antibody (Alexa Fluor 488)

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Binding Specificity: AA 401-500

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SORBS2/ArgBP2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: SORBS2 (Sorbs2 Products)

Synonyms: Argbp2 antibody, 2010203O03Rik antibody, 9430041O17Rik antibody, A530071H08 antibody, mKIAA0777 antibody, argbp2 antibody, pro0618 antibody, 9430041O17RIK antibody, DKFZp468F1119 antibody, ARGBP2 antibody, PRO0618 antibody, sorbin and SH3 domain containing 2 antibody, Sorbs2 antibody, SORBS2 antibody, sorbs2 antibody

Background:

Synonyms: ARGBP2, PRO618, Sorbin and SH3 domain-containing protein 2, Arg/Abl-interacting protein 2, Sorbin, SORBS2, KIAA777

Background: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Gene ID: 8470

UniProt: O94875