SF3A2 antibody (AA 65-160) (Alexa Fluor 350)

Catalog No. ABIN1397862

Product Details anti-SF3A2 Antibody (Alexa Fluor 350)

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Binding Specificity: AA 65-160

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3A2 antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SAP62

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SF3A2

Target: SF3A2 (Splicing Factor 3a, Subunit 2, 66kDa (SF3A2))

Alternative Name: SAP62 (SF3A2 Products)

Background:

Synonyms: PRP11, SAP62, PRPF11, SF3a66, Splicing factor 3A subunit 2, Spliceosome-associated protein 62, SAP 62, SF3A2

Background: Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.

Gene ID: 8175

UniProt: Q15428

Pathways: Ribonucleoprotein Complex Subunit Organization