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MMS19 antibody (AA 851-950) (Alexa Fluor 350)

MMS19 Reactivity: Human, Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1400097
  • Target See all MMS19 Antibodies
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    Binding Specificity
    • 14
    • 7
    • 1
    • 1
    • 1
    • 1
    AA 851-950
    Reactivity
    • 29
    • 17
    • 3
    Human, Mouse
    Host
    • 25
    • 4
    Rabbit
    Clonality
    • 27
    • 2
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMS19 antibody is conjugated to Alexa Fluor 350
    Application
    • 29
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse
    Predicted Reactivity
    Rat,Dog,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MMS 19
    Isotype
    IgG
    Top Product
    Discover our top product MMS19 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MMS19 (MMS19 Nucleotide Excision Repair Homolog (MMS19))
    Alternative Name
    MMS19 (MMS19 Products)
    Synonyms
    MET18 antibody, MMS19L antibody, hMMS19 antibody, 2410001K24Rik antibody, 2610042O15Rik antibody, AI316855 antibody, C79368 antibody, C86341 antibody, Mms19l antibody, mms19 antibody, mms19l antibody, MMS19 homolog, cytosolic iron-sulfur assembly component antibody, MMS19 (MET18 S. cerevisiae) antibody, MMS19 homolog, cytosolic iron-sulfur assembly component L homeolog antibody, MMS19 antibody, Mms19 antibody, mms19.L antibody
    Background

    Synonyms: MET18, MMS19L, hMMS19, MMS19 nucleotide excision repair protein homolog, MET18 homolog, MMS19-like protein, MMS19

    Background: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.

    Gene ID
    64210
    UniProt
    Q96T76
    Pathways
    Nuclear Hormone Receptor Binding
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