ANKS1B antibody (Alexa Fluor 350)

Catalog No. ABIN1400817

Product Details anti-ANKS1B Antibody (Alexa Fluor 350)

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANKS1B antibody is conjugated to Alexa Fluor 350

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKS1B/AIDA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ANKS1B

Target: ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))

Alternative Name: ANKS1B (ANKS1B Products)

Synonyms: AIDA antibody, AIDA-1 antibody, ANKS2 antibody, EB-1 antibody, EB1 antibody, cajalin-2 antibody, AIDA-1b antibody, C030032C09Rik antibody, E530015N03Rik antibody, ENSMUSG00000078431 antibody, Gm10937 antibody, Gm1555 antibody, RGD1565556 antibody, si:ch211-146a9.3 antibody, si:dkey-11k24.3 antibody, Anks1b antibody, ankyrin repeat and sterile alpha motif domain containing 1B antibody, ankyrin repeat and sterile alpha motif domain-containing protein 1B antibody, ANKS1B antibody, Anks1b antibody, anks1b antibody, LOC100717398 antibody

Background:

Synonyms: AIDA 1, AIDA-1, Amyloid-beta protein intracellular domain-associated protein 1, Anks1b, Ankyrin repeat and sterile alpha mot domain-containing protein 1B, ANS1B_HUMAN, E2A-PBX1-associated protein, EB-1.

Background: The _-Amyloid protein precursor (AbPP) is a widely expressed transmembrane protein that is processed into the b-Amyloid (Ab) peptide, which accumulates in insoluble plaques in the brain of Alzheimer?s disease patients and AbPP intracellular domain (AID). AID may function as a pro-apoptotic peptide, a regulator of calcium homeostasis and a molecule involved in transcriptional regulation. The AID associated protein 1 (AIDA-1) is highly expressed in the brain and is regulated by AbPP. It interacts with AbPP to play a role in brain development. AIDA-1 also interacts with coilin in Cajal bodies to regulate pre-mRNA splicing.

Gene ID: 56899

UniProt: Q7Z6G8