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SERPINE2 antibody (AA 301-398) (Alexa Fluor 350)

SERPINE2 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1404993
  • Target See all SERPINE2 Antibodies
    SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))
    Binding Specificity
    • 14
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 301-398
    Reactivity
    • 50
    • 23
    • 20
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 34
    • 17
    • 2
    • 2
    • 1
    Rabbit
    Clonality
    • 40
    • 16
    Polyclonal
    Conjugate
    • 29
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SERPINE2 antibody is conjugated to Alexa Fluor 350
    Application
    • 47
    • 25
    • 19
    • 12
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GDN/SERPINE2
    Isotype
    IgG
    Top Product
    Discover our top product SERPINE2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SERPINE2 (serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2))
    Alternative Name
    GDN (SERPINE2 Products)
    Synonyms
    GDN antibody, GDNPF antibody, PI-7 antibody, PI7 antibody, PN-1 antibody, PN1 antibody, PNI antibody, SERPINE2 antibody, MGC143011 antibody, Gdnpn1 antibody, Pn-1 antibody, Spin4 antibody, B230326M24Rik antibody, PAI-1 antibody, Spi4 antibody, zgc:55929 antibody, serpin family E member 2 antibody, serine (or cysteine) peptidase inhibitor, clade E, member 2 antibody, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 antibody, SERPINE2 antibody, serpine2 antibody, Serpine2 antibody
    Background

    Synonyms: Glia derived nexin, Protease inhibitor 7, GDN, GDN_HUMAN, Glia-derived nexin, P17 antibody Peptidase inhibitor 7, Pi-7, Plasminogen activator inhibitor type 1, member 2, PN-1, PN1, PNI, Protease nexin 1, Protease nexin I, Serpin E2, Serpin peptidase inhibitor, clade E nexin, plasminogen activator inhibitor type 1, member 2, SERPINE 2, Serpine2.

    Background: The serine protease inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Protease nexin-1 (PN-1) is a serpin that inactivates several proteases, including thrombin, urokinase, plasminogen activators (PA) and plasmin. It is involved in tissue remodeling, cellular invasiveness, matrix degradation and tumor growth. PN-1 expression is abundant in the nervous system, where it inhibits thrombin, thereby playing a role in neural injury and repair processes. An imbalance between PN-1 and thrombin may be a contributing factor in the pathology of Alzheimer??s disease.

    Gene ID
    5270
    UniProt
    P07093
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