HSPA4 antibody (Biotin)

Catalog No. ABIN1405051

Product Details anti-HSPA4 Antibody (Biotin)

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA4 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP_7/cvHSP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSPA4

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Alternative Name: HSP_7 (HSPA4 Products)

Synonyms: APG-2 antibody, HS24/P52 antibody, HSPH2 antibody, RY antibody, hsp70 antibody, hsp70RY antibody, Hsp110 antibody, Hsp70 antibody, irp94 antibody, 70kDa antibody, AI317151 antibody, Hsp70RY antibody, mKIAA4025 antibody, hspa4 antibody, wu:fi30e11 antibody, zgc:55743 antibody, zgc:77413 antibody, hs24/p52 antibody, hspa4-a antibody, osp94 antibody, pg-2 antibody, hspa4l antibody, wu:fc41d05 antibody, wu:fi59h02 antibody, wu:fj35c08 antibody, zgc:55506 antibody, heat shock protein family A (Hsp70) member 4 antibody, heat shock protein family A member 4 antibody, heat shock protein 4 antibody, heat shock protein 4b antibody, heat shock protein family A (Hsp70) member 4 S homeolog antibody, heat shock protein 4a antibody, HSPA4 antibody, Hspa4 antibody, hspa4b antibody, hspa4.S antibody, hspa4a antibody

Background:

Synonyms: Cardiovascular heat shock protein, cvHsp, Heat shock 27kda protein family member 7, Heat shock protein beta 7, Heat shock protein beta-7, Hsp25 2, HspB7, HSPB7_HUMAN, Hypothetical protein flj34956, RP11-5P18.6

Background: The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the small HSPs, the immunophilins and the HSP 110 family. HSPB7 (heat shock 27 kDa protein family, member 7), also known as cvHSP (cardiovascular heat shock protein) or Heat shock protein beta-7, is a member of the small HSP (sHSP) family expressed in heart and skeletal muscle. Members of the sHSP family contain a conserved C-terminal ?crystallin domain and typically function in homo- or heteromeric complexes. The sHSPs bind to denatured proteins and are responsible for preventing the aggregation of these proteins. In response to muscle fiber transformation and in muscular dystrophy, the expression levels of HSPB7 are drastically increased, suggesting that HSPB7 may be a useful target in therapeutic strategies for preventing age-related muscle wasting.

Gene ID: 27129