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RP1 antibody (AA 451-550) (HRP)

RP1 Reactivity: Human IHC (fro), IHC (p), ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN1406750
  • Target See all RP1 Antibodies
    RP1 (Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1))
    Binding Specificity
    AA 451-550
    Reactivity
    Human
    Host
    • 14
    Rabbit
    Clonality
    • 14
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RP1 antibody is conjugated to HRP
    Application
    • 13
    • 13
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RP1/Oxygen-regulated protein 1
    Isotype
    IgG
    Top Product
    Discover our top product RP1 Primary Antibody
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    RP1 (Retinitis Pigmentosa 1 (Autosomal Dominant) (RP1))
    Alternative Name
    Oxygen-regulated protein 1 (RP1 Products)
    Synonyms
    orp1 antibody, MGC83581 antibody, DCDC4A antibody, ORP1 antibody, Rp1h antibody, Dcdc3 antibody, Orp1 antibody, mG145 antibody, RP1, axonemal microtubule associated L homeolog antibody, RP1, axonemal microtubule associated antibody, retinitis pigmentosa 1 (autosomal dominant) antibody, uncharacterized LOC100355685 antibody, retinitis pigmentosa 1 (human) antibody, rp1.L antibody, RP1 antibody, rp1 antibody, LOC100355685 antibody, Rp1 antibody
    Background

    Synonyms: DCDC4A, ORP1, Oxygen-regulated protein 1, Retinitis pigmentosa 1 protein, Retinitis pigmentosa RP1 protein, RP1, RP1_HUMAN.

    Background: Retinitis pigmentosa 1 is a novel 2,156 amino acid oxygen-regulated photoreceptor specific to retina. Originally named ORP1 (for 'oxygen-regulated protein-1'), the expression of retinitis pigmentosa 1 has been found to be regulated by oxygen levels in the retina. Mutation of the retinitis pigmentosa 1 gene causes dominant retinitis pigmentosa which leads to degeneration of retinal photoreceptor cells and symptoms such as night vision blindness and deficits in the midperipheral visual field. Retinitis pigmentosa 1 may assist in differentiation of photoreceptor cells and has been identified in the cilia of photoreceptors, possibly aiding in both cilial structure and protein transport between inner and outer segments of photoreceptors. Retinitis pigmentosa 1 contains two doublecortin domains and is encoded by a gene which maps to human chromosome 8q11-q13.

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