ZNF461 antibody (AA 191-240) (HRP)

Catalog No. ABIN1408982

Product Details anti-ZNF461 Antibody (HRP)

Target: ZNF461 (Zinc Finger Protein 461 (ZNF461))

Binding Specificity: AA 191-240

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF461 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIOT1/ZNF461 (191-240aa)

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZNF461

Target: ZNF461 (Zinc Finger Protein 461 (ZNF461))

Alternative Name: GIOT1/ZNF461 (ZNF461 Products)

Synonyms: GIOT-1 antibody, GIOT1 antibody, zinc finger protein 461 antibody, ZNF461 antibody

Background:

Synonyms: GIOT-1, GIOT 1, Gonadotropin inducible ovary transcription repressor 1, Gonadotropin inducible transcription repressor 1, Gonadotropin-inducible ovary transcription repressor 1, Zinc finger protein 461, ZN461_HUMAN, ZNF461.

Background: GIOT-1 is a 563 amino acid protein belonging to the Kr_ppel C2H2-type zinc-finger protein family. Localized to the nucleus, GIOT-1 is widely expressed in tissues, with highest levels in liver, kidney, small intestine, pancreas and thymus. GIOT-1 contains 12 C2H2-type zinc fincers and one KRAB domain. Because the KRAB domain functions as a transcriptional repressor when attached to the template DNA, GIOT-1 is thought to be involved in transcriptional regulation. The gene encoding GIOT-1 is localized to chromosome 19q13.12 and two isoforms of GIOT-1 exist as a result of alternative splicing events.

Gene ID: 92283