DOCK7 antibody (AA 1401-1500) (HRP)

Catalog No. ABIN1411442

Product Details anti-DOCK7 Antibody (HRP)

Target: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Binding Specificity: AA 1401-1500

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK7 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DOCK7

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DOCK7

Target: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Alternative Name: DOCK7 (DOCK7 Products)

Synonyms: im:7145816 antibody, im:7157388 antibody, wu:fb93h07 antibody, ZIR2 antibody, 3110056M06Rik antibody, Gm430 antibody, m antibody, mKIAA1771 antibody, dedicator of cytokinesis 7 antibody, dedicator of cytokinesis protein 7 antibody, dedicator of cytokinesis 6 antibody, DOCK7 antibody, dock7 antibody, NAEGRDRAFT_56982 antibody, LOC100185115 antibody, dock6 antibody, Dock7 antibody

Background:

Synonyms: dedicator of cytokinesis 7, Dedicator of cytokinesis protein 7, Gm430, KIAA1771 , MGC189434, mKIAA1771, RP23 329P19.2, ZIR2, DOCK7_HUMAN.

Background: DOCK 7 is a 2,140 amino acid protein that localizes to developing axons and contains one DHR-1 domain and one DHR-2 domain. Expressed in a variety of tissues, DOCK 7 functions as a guanine nucleotide exchange factor (GEF) that specifically activates Rac 1 and Rac 3 by catalyzing the exchange of bound GDP for free GTP. Multiple isoforms of DOCK 7 exist due to alternative splicing events.

Gene ID: 85440

UniProt: Q96N67