METRN antibody (AA 101-200) (HRP)

Catalog No. ABIN1411802

Product Details anti-METRN Antibody (HRP)

Target: METRN (Meteorin, Glial Cell Differentiation Regulator (METRN))

Binding Specificity: AA 101-200

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This METRN antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human METRN

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for METRN

Target: METRN (Meteorin, Glial Cell Differentiation Regulator (METRN))

Alternative Name: METRN (METRN Products)

Synonyms: mtrn antibody, zgc:92132 antibody, wu:fb81a08 antibody, METRN antibody, C16orf23 antibody, c380A1.2 antibody, Hyrac antibody, RGD1306222 antibody, 1810034B16Rik antibody, meteorin, glial cell differentiation regulator antibody, meteorin antibody, METRN antibody, metrn antibody, Metrn antibody

Background:

Synonyms: C16orf23, c380A1.2, Meteorin, Meteorin precursor, meteorin, glial cell dferentiation regulator, Metrn, METRN_HUMAN, MGC2601.

Background: Meteorin is a secreted protein belonging to the Meteorin family that contains 293 amino acids and promotes axonal extension, axonal network formation and regulates glial cell differentiation. Expressed in radial glia and undifferentiated neural progenitors of the central and peripheral nervous system, Meteorin is encoded by a gene located on human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN (Gigaxonin) gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.