RENBP antibody (AA 101-200) (Cy5)

Catalog No. ABIN1417254

Product Details anti-RENBP Antibody (Cy5)

Target: RENBP (Renin Binding Protein (RENBP))

Binding Specificity: AA 101-200

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RENBP antibody is conjugated to Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RENBP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for RENBP

Target: RENBP (Renin Binding Protein (RENBP))

Alternative Name: RENBP (RENBP Products)

Synonyms: RBP antibody, RNBP antibody, Age antibody, Rnbp antibody, RnBP antibody, AGE antibody, RENBP antibody, MGC114748 antibody, wu:fc36a08 antibody, zgc:103475 antibody, renin binding protein antibody, renin binding protein L homeolog antibody, RENBP antibody, Renbp antibody, renbp.L antibody, renbp antibody, TVAG_270790 antibody

Background:

Synonyms: AGE, EC 5.1.3.8, GlcNAc 2 epimerase, GlcNAc 2-epimerase, N acetyl D glucosamine 2 epimerase, N-acetyl-D-glucosamine 2-epimerase, N-acylglucosamine 2-epimerase, RBP, RENBP, RENBP_HUMAN, Renin binding protein, Renin-binding protein, RNBP.

Background: RENBP is a 427 amino acid protein that is a proteinaceous renin inhibitor. In inhibiting renin, RENBP forms a complex with it, a high molecular weight renin. RENBP contains a leucine zipper domain, which is essential for its dimerization with renin. RENBP can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Sequences of porcine, human and rat renin-binding proteins are highly homologous. The RENBP gene is conserved in dog, mouse, rat and zebrafish, and maps to human chromosome Xq28 between DXS52 and G6PD. Rat Renbp is located on chromosome X at Xq37 close to marker DXWox3 and falls outside the BP QTL regions on chromosome X.

Gene ID: 5973