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SPP2 antibody (AA 55-160) (HRP)

SPP2 Reactivity: Rat WB, IHC (p), ELISA, IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1417384
  • Target See all SPP2 Antibodies
    SPP2 (Secreted Phosphoprotein 2 (SPP2))
    Binding Specificity
    • 14
    • 1
    AA 55-160
    Reactivity
    • 14
    • 2
    Rat
    Host
    • 15
    • 1
    Rabbit
    Clonality
    • 15
    • 1
    Polyclonal
    Conjugate
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPP2 antibody is conjugated to HRP
    Application
    • 16
    • 13
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPP24/SPP2
    Isotype
    IgG
    Top Product
    Discover our top product SPP2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    SPP2 (Secreted Phosphoprotein 2 (SPP2))
    Alternative Name
    SPP24 (SPP2 Products)
    Synonyms
    spp24 antibody, 0610038O04Rik antibody, pp-24 antibody, SPP-24 antibody, SPP24 antibody, GHRG-1 antibody, secreted phosphoprotein 2 antibody, spp2 antibody, Spp2 antibody, SPP2 antibody
    Background

    Synonyms: SPP24, SPP-24, Secreted phosphoprotein 24, Secreted phosphoprotein 2, SPP2

    Background: SPP24, also known as secreted phosphoprotein 2, is a 211 amino acid secreted protein that belongs to the cystatin superfamily. Expressed in liver and plasma, SPP24 may play a role in coordinating an aspect of bone turnover. The gene that encodes SPP24 maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes, making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

    Gene ID
    6694
    UniProt
    Q13103
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