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Ataxia Telangiectasia and Rad3 Related (ATR) antibody

Details for Product No. ABIN143628
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Antigen
Synonyms
FCTCS, FRP1, MEC1, SCKL, SCKL1, XATR, frp1, mec1, sckl, sckl1, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, ATATR, ATRAD3, Ataxia telangiectasia-mutated and RAD3-related, MHK7. ... show more
FCTCS, FRP1, MEC1, SCKL, SCKL1, XATR, frp1, mec1, sckl, sckl1, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, ATATR, ATRAD3, Ataxia telangiectasia-mutated and RAD3-related, MHK7.5, MHK7_5, ATR, si:dkey-231j24.1 show less
Reactivity
Human
(20), (8), (4), (2), (2), (1), (1), (1), (1)
Host
Rabbit
(17), (6)
Clonality
Polyclonal
Application
Immunoprecipitation (IP), Western Blotting (WB)
(16), (7), (6), (2), (2)
Pubmed 1 reference available
Quantity 50 µL
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Catalog No. ABIN143628
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Immunogen The carboxy-terminal portion of human ATR protein (amino acids 2122-2644).
Isotype IgG
Alternative Name ATR / FRP1
Background Ataxia Telangiectasia Mutated (ATM) and Rad3-related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.
Application Notes Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Restrictions For Research Use only
Format Liquid
Buffer Anti-serum with 0.09% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -80 °C
General Abraham: "Cell cycle checkpoint signaling through the ATM and ATR kinases." in: Genes & development, Vol. 15, Issue 17, pp. 2177-96, 2001 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN143628
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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