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Details for Product No. ABIN143628

Ataxia Telangiectasia and Rad3 Related (ATR) antibody

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Antigen
Synonyms
FCTCS, FRP1, MEC1, SCKL, SCKL1, XATR, frp1, mec1, sckl, sckl1, ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, ATATR, ATRAD3, Ataxia telangiectasia-mutated and RAD3-related, MHK7. ... show more
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN143628
Quantity 50 µL
Price
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Immunogen The carboxy-terminal portion of human ATR protein (amino acids 2122-2644).
Isotype IgG
Alternative Name ATR / FRP1
Background Ataxia Telangiectasia Mutated (ATM) and Rad3-related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.
Application Notes Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
Restrictions For Research Use only
Buffer Anti-serum with 0.09% sodium azide.
Preservative Sodium azide
Storage -80 °C
Abraham: "Cell cycle checkpoint signaling through the ATM and ATR kinases." in: Genes & development, Vol. 15, Issue 17, pp. 2177-96, 2001 (PubMed).

Alternatives for antigen "Ataxia Telangiectasia and Rad3 Related (ATR)", type "Antibodies"
Hosts (21), (7), (1)
Reactivities (26), (9), (4), (2), (2), (1), (1), (1), (1)
Applications (20), (8), (7), (5), (3), (1)
Epitopes (3), (2), (1), (1), (1), (1), (1), (1)
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