Ataxia Telangiectasia and Rad3 Related (ATR) antibody
| Antigen |
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| Synonyms |
FRP1, MEC1, SCKL, SCKL1, ATR, atr, XATR, frp1, mec1, sckl, sckl1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunoprecipitation (IP), Western Blotting (WB)
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| Catalog no. |
ABIN143628 |
| Quantity |
50 µl (Variants) |
| Price |
Product not available in this region.
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| Shipping to |
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Alternative name
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ATR / FRP1
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Immunogen
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The carboxy-terminal portion of human ATR protein (amino acids 2122-2644).
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Cross-Reactivity
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Human
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Isotype
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IgG
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Description
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Ataxia Telangiectasia Mutated (ATM) and Rad3-related (ATR) protein is a member of the phosphatidyl-inositol 3-kinase (PI 3-kinase) like family of protein kinases. ATR has a predicted molecular mass of approximately 301 kDa, and it has been shown to be involved in cellular responses to DNA damage. Specifically, it plays a role in checkpoint activation in response to either the presence of stalled replication forks, or by the presence of lesions caused by UV light. Inactivation of ATR is an embryonic lethal event in mice.
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Application Notes
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Not tested in other applications. Optimal dilutions/concentrations should be determined by the researcher.
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Buffer
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Anti-serum with 0.09% sodium azide.
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Storage
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For long term storage, please keep at -70 C or below. Avoid repeared freeze-thaw cycles.
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Restrictions
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For Research Use only
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Abraham: "Cell cycle checkpoint signaling through the ATM and ATR kinases." in: Genes & development, Vol. 15, Issue 17, pp. 2177-96, 2001 (PubMed).
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Alternatives for antigen "Ataxia Telangiectasia and Rad3 Related (ATR)", type "Antibodies"
2013 BioMed Central Research Awards
