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Product details for Hematopoiesis related Macrophage (Mouse) antibody
Hematopoiesis related Macrophage (Mouse) antibody
Overview
| Antigen: | Hematopoiesis related Macrophage |
| Antibody Type: | Polyclonal |
| Application: | Flow Cytometry (FACS), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Reactivity: | Mouse (Murine) |
| Host: | Rat |
| Quantity: | |
| Price: | 291,00 € (Plus shipping costs and VAT) |
| Order number: | ABIN144847 |
| Availability: | 7 to 10 days until shipment |
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Additional Information: Hematopoiesis related Macrophage (Mouse) antibody
| Antigen | Hematopoiesis related Macrophage |
| Immunogen | Adherent bone marrow cells. |
| Reactivity | Mouse (Murine) |
| Antibody Type | Polyclonal |
| Format | Liquid |
| Isotype | IgG2c |
| Description | Macrophage are any of the many forms of mononuclear phagocytes found in tissues. Mononuclear phagocytes arise from hematopoietic stem cells in the bone marrow. After passing through the monoblast and promonocyte states of the monocyte stage, they enter the blood, circulating for about 40 hours. They then enter tissues and increase in size, phagocytic activity, and lysosomal enzyme content and become macrophages. The morphology of macrophages varies among different tissues and between normal and pathologic states, and not all macrophages can be identified by morphology alone. However, most macrophages are large cells with a round or indented nucleus, a well developed Golgi apparatus, abundant endocytotic vacuoles, lysosomes, and phagolysosomes, and a plasma membrane covered with ruffles or microvilli. Among the functions of macrophages are nonspecific phagocytosis and pinocytosis, specific phagocytosis of opsonized microorganisms mediated by Fc receptors and complement receptors, kil |
| Clone | ER-HR3 |
| Host | Rat |
| Specificity | Ab15636 recognises the majority of blood monocytes and a subset of mature resident macrophages, especially those located in hemopoietic organs. Does not cross react with other leukocytes.The antigen is found on up to 70% of circulating monocytes, all othe |
| Secondary Antibodies | Chicken anti-Rat IgG, Donkey anti-Rat IgG, Goat anti-Rat IgG, Mouse anti-Rat IgG, Rabbit anti-Rat IgG, Sheep anti-Rat IgG |
Application Details: Hematopoiesis related Macrophage (Mouse) antibody
| Application | Flow Cytometry (FACS), Immunohistochemistry ((Frozen Sections) (IHC) (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
| Application Notes | FACS: Use at a dilution of 1/25-1/50. IHC-P: Use at a concentration of 50 ug/ml (1:20). IHC-Fr (acetone): Use at a concentration of 10 ug/ml (1:100). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Format | Liquid |
| Concentration | 1 mg/ml |
| Purity | Protein G purified |
| Buffer | Preservative: 0.01% ThimerosalConstituents: PBS, 10mg/ml BSA. pH 7.2 |
| Storage | Store at 4C. Aliquot and store at -20C long-term. |
| Restrictions | For research use only |
External Information: Hematopoiesis related Macrophage (Mouse) antibody
| Google Scholar | Find more references for clone ER-HR3 on Google Scholar™ |
| EMBL Harvester | Search human, mouse or rat genome for antigen Hematopoiesis related Macrophage (Bioinformatic Harvester (EMBL)) |
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