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PD-L1 antibody (Extracellular Domain) (PE)

PD-L1 Reactivity: Human FACS Host: Mouse Monoclonal J1050 PE
Catalog No. ABIN1449174
  • Target See all PD-L1 Antibodies
    PD-L1 (CD274 (PD-L1))
    Binding Specificity
    • 29
    • 16
    • 15
    • 13
    • 11
    • 11
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivity
    • 167
    • 106
    • 63
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    Human
    Host
    • 126
    • 59
    • 15
    • 4
    • 4
    • 1
    Mouse
    Clonality
    • 108
    • 99
    • 2
    Monoclonal
    Conjugate
    • 97
    • 14
    • 13
    • 11
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    This PD-L1 antibody is conjugated to PE
    Application
    • 137
    • 102
    • 60
    • 40
    • 36
    • 28
    • 17
    • 16
    • 16
    • 15
    • 10
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody reacts with human PD-1.
    Purification
    Protein A agarose
    Immunogen
    Fusion protein of the extracellular domain of human PD-1 and the constant region of human gamma1 heavy chain
    Clone
    J1050
    Isotype
    IgG1
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS, 0.09 % NaN3, 1 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8 °C.
  • Target
    PD-L1 (CD274 (PD-L1))
    Alternative Name
    CD274 / PDL1 (PD-L1 Products)
    Synonyms
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    Background
    Human PD-1 (programmed death-1) is a 55 kDa member of the immunoglobulin superfamily that is induced in cells that are undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
    Gene ID
    29126
    NCBI Accession
    NP_054862
    UniProt
    Q9NZQ7
    Pathways
    Cancer Immune Checkpoints
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