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SYT2 antibody (N-Term)

SYT2 Reactivity: Rat WB, IP Host: Mouse Monoclonal 8G2 unconjugated
Catalog No. ABIN1449191
  • Target See all SYT2 Antibodies
    SYT2 (Synaptotagmin II (SYT2))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-20, N-Term
    Reactivity
    • 32
    • 17
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Host
    • 29
    • 2
    • 2
    • 1
    Mouse
    Clonality
    • 32
    • 2
    Monoclonal
    Conjugate
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SYT2 antibody is un-conjugated
    Application
    • 25
    • 18
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Sequence
    MRNIFKRNQE PIVAPATTTA
    Specificity
    This antibody reacts with Synaptotagmin 2.
    Cross-Reactivity (Details)
    Species reactivity (tested):Rat
    Immunogen
    Synthesized peptide which corresponding to rat synaptotagmin 2 N-terminus (1-20 aa)
    Clone
    8G2
    Isotype
    IgG1
    Top Product
    Discover our top product SYT2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
    Preservative
    Without preservative
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    SYT2 (Synaptotagmin II (SYT2))
    Alternative Name
    Synaptotagmin-2 (SYT2 Products)
    Synonyms
    SytII antibody, RATSYNII antibody, SYNII antibody, R74640 antibody, mKIAA4194 antibody, si:ch211-236j4.1 antibody, synaptotagmin 2 antibody, synaptotagmin II antibody, synaptotagmin IIa antibody, SYT2 antibody, Syt2 antibody, syt2a antibody, syt2 antibody
    Background
    Synaptotagmins are a family of at least 15 Ca2+-binding, membrane-trafficking proteins that act as calcium sensors regulating neurotransmitter release. Synaptotagamins are expressed in both vesicular and plasma membranes where they are involved in lipid rearrangements required during synaptic vesicle fusion. Synaptotagmins also interact with calcium channels, sodium channels, ß-SNAP, neurexins, and other neural proteins in the absence of Ca2+, suggesting a role in presynaptic functions. Synaptotagmins exhibit differential expression, with synaptotagmins 1-5 expressed primarily in neural and endocrine tissues. Northern blots in murine brain tissue suggest synaptotagmin 1 is primarily expressed in rostral brain regions but has low expression in regions related to motor functions.Synonyms: SYT-2, SYT2, SYTII, Synaptotagmin 2, Synaptotagmin II
    Molecular Weight
    60 kDa
    Gene ID
    127833
    NCBI Accession
    NP_001129976
    UniProt
    Q8N9I0
    Pathways
    Synaptic Vesicle Exocytosis
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