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TNFRSF13C antibody
TNFRSF13C
Reactivity: Human
WB, FACS, IHC (p)
Host: Mouse
Monoclonal
8A7
unconjugated
Product Details anti-TNFRSF13C Antibody
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Target
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TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Reactivity
All reactivities for TNFRSF13C antibodies
Human
Host
All hosts for TNFRSF13C antibodies
Mouse
Clonality
All clonalities for TNFRSF13C antibodies
Monoclonal
Conjugate
All conjugates for TNFRSF13C antibodies
This TNFRSF13C antibody is un-conjugated
Application
All applications for TNFRSF13C antibodies
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody reacts with human BAFF-R/BR3.
Purification
Protein A agarose
Immunogen
Human BAFF-R/BR3 transfectant
Clone
8A7
Isotype
IgG2a
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Discover our top product TNFRSF13C Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Upon receipt, store (in aliqouts) at -20 °C.
Target Details for TNFRSF13C
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Target
TNFRSF13C
(Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C))
Alternative Name
CD268 / BAFFR (TNFRSF13C Products )
Synonyms
RGD1560810 antibody, TNFRSF13C antibody, BAFF-R antibody, BAFFR antibody, BROMIX antibody, CD268 antibody, CVID4 antibody, prolixin antibody, 2010006P15Rik antibody, Baffr antibody, Bcmd antibody, Bcmd-1 antibody, Bcmd1 antibody, Lvis22 antibody, TNF receptor superfamily member 13C antibody, uncharacterized LOC746611 antibody, tumor necrosis factor receptor superfamily, member 13c antibody, TNFRSF13C antibody, Tnfrsf13c antibody, LOC746611 antibody
Background
BAFF (B cell-activating factor belonging to the TNF family) is a membrane protein expressed by dendritic cells, monocytes, macrophages, follicular dendritic cells, activated T cells, activated neutrophils, and malignant B cells. BAFF, also known as BLyS (B lymphocyte stimulator), is a potent B cell growth factor. Proteolytic cleavage can result in the release of a soluble trimeric BAFF which binds to the BAFF-R/BR3, BCMA and TACI. BAFF-R/BR3 is the principal receptor for B cell survival and responses induced by BAFF.Synonyms: B cell-activating factor receptor, BAFF receptor, BAFF-R, BLyS receptor 3, BR3, TNFRSF13C, Tumor necrosis factor receptor superfamily member 13C
Gene ID
115650
NCBI Accession
NP_443177
UniProt
Q96RJ3
Pathways
NF-kappaB Signaling
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