Histone H1 antibody
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- Target See all Histone H1 (H1F0) Antibodies
- Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))
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Reactivity
- Human, Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Histone H1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
- Specificity
- This antibody reacts with Histone H1.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse, Rat
- Purification
- Protein A agarose
- Immunogen
- Protein fraction extracted from the mitotic chromosome
- Clone
- C14093
- Isotype
- IgG2b
- Top Product
- Discover our top product H1F0 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
- Preservative
- Without preservative
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Upon receipt, store (in aliqouts) at -20 °C.
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- Target
- Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))
- Alternative Name
- Histone H1.0 (H1F0 Products)
- Synonyms
- H5 antibody, h10 antibody, h1fv antibody, fb23b02 antibody, wu:fb23b02 antibody, zgc:65861 antibody, H1F0 antibody, H1fv antibody, H10 antibody, H1FV antibody, D130017D06Rik antibody, H1(0) antibody, h1(0)-1 antibody, h1f0 antibody, H1 antibody, H1 histone family member 0 antibody, H1 histone family, member 0 antibody, histone H1.0 antibody, H1 histone family member 0 S homeolog antibody, H1 histone family member 0 L homeolog antibody, histone I antibody, h1f0 antibody, H1F0 antibody, LOC698693 antibody, H1f0 antibody, h1f0.S antibody, h1f0.L antibody, his1 antibody
- Background
- The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The N-terminal tail of core histones undergoes multiple different post-translational modifications including acetylation, phosphorylation, ubiquitination, methylation, and ADP-ribosylation. Histone H1, also known as linker histone, is bound to linker DNA region between nucleosomes, contributing to chromatin foldings in nucleus. It is known that histone H1 is also post-translationally modified, such as phosphorylation or methylation and relation of these modifications with biological meanings are under extensive investigations. Histone H1 is essential for higher order structure of mitotic chromosomes that are condensed structure of chromatin during mitosis.Synonyms: H1F0, H1FV, Histone H1', Histone H1(0)
- Molecular Weight
- 32 kDa
- Gene ID
- 3005
- NCBI Accession
- NP_005309
- UniProt
- P07305
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