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FOXP3 antibody (FITC)

FOXP3 Reactivity: Mouse FACS Host: Rat Monoclonal MF-14 FITC
Catalog No. ABIN1449249
  • Target See all FOXP3 Antibodies
    FOXP3 (Forkhead Box P3 (FOXP3))
    Reactivity
    • 155
    • 113
    • 46
    • 25
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 116
    • 58
    • 11
    • 2
    Rat
    Clonality
    • 116
    • 71
    Monoclonal
    Conjugate
    • 89
    • 18
    • 12
    • 12
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This FOXP3 antibody is conjugated to FITC
    Application
    • 133
    • 83
    • 70
    • 38
    • 37
    • 27
    • 27
    • 19
    • 18
    • 17
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    This antibody reacts with mouse Foxp3.
    Purification
    Protein G agarose
    Immunogen
    Recombinant full-length mouse Foxp3
    Clone
    MF-14
    Isotype
    IgG2b
    Top Product
    Discover our top product FOXP3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    50 tests in 1 mLvolume of PBS containing 1 % BSA and 0.09 % NaN3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 2-8 °C.
  • Target
    FOXP3 (Forkhead Box P3 (FOXP3))
    Alternative Name
    FOXP3 (FOXP3 Products)
    Synonyms
    foxp3 antibody, FOXP3 antibody, AIID antibody, DIETER antibody, IPEX antibody, PIDX antibody, XPID antibody, JM2 antibody, scurfin antibody, sf antibody, RGD1562112 antibody, forkhead box P3 antibody, forkhead box P3a antibody, forkhead box P3 L homeolog antibody, FOXP3 antibody, foxp3a antibody, foxp3 antibody, foxp3.L antibody, Foxp3 antibody
    Background
    Forkhead-winged helix P3 (Foxp3), also known as Scurfin or JM2, is a 50-55 kDa transcription factor, originally identified as the gene defective in Scurfy mice. Scurfy mice and humans with similar mutations spontaneously develop autoimmune diseases (IPEX). Resent reports revealed that Foxp3 is expressed in CD4 + CD25 + regulatory T cells (Treg cells), and ectopic expression of Foxp3 in CD4 + Foxp3 - T cells induced a Treg-like phenotype in these cells. Importantly, these reports indicate that Foxp3 is a specific marker for Treg cells. Taken together, Foxp3 is believed to be a crucial regulator of the development and function of Treg cells.Synonyms: Forkhead box protein P3, IPEX, JM2, Scurfin
    Gene ID
    20371
    NCBI Accession
    NP_001186276
    UniProt
    Q99JB6
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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