Ubiquitin antibody

Details for Product No. ABIN1449301
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Antigen
Synonyms
CG11624, DmUb, DmUbi-p63E, Dmel\\CG11624, Ub, Ubi-P63e, Ubi-p, Ubi63E, Ubi63p, Ubip, Ubiq, Ubp, ubi, ubi-p63E, ubi63E, CG18282, CG32744, CR32744, DmUbi-p5E, Dmel\\CG32744, ubiquitin, si:dz180g5.5, si: ... show more
CG11624, DmUb, DmUbi-p63E, Dmel\\CG11624, Ub, Ubi-P63e, Ubi-p, Ubi63E, Ubi63p, Ubip, Ubiq, Ubp, ubi, ubi-p63E, ubi63E, CG18282, CG32744, CR32744, DmUbi-p5E, Dmel\\CG32744, ubiquitin, si:dz180g5.5, si:busm1-180g5.5, LOC100194618, UBIQ, Ubiquitin, LOC100282068 show less
Reactivity
Cow (Bovine), Human
(148), (108), (55), (55), (15), (12), (9), (8), (6), (6), (6), (6), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Host
Mouse
(136), (115), (3), (2), (2), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(9), (6), (5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(181), (126), (82), (65), (37), (32), (24), (23), (12), (10), (2), (1)
Pubmed 8 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN1449301
357.50 $
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Immunogen Bovine erythrocyte ubiquitin
Clone 1B3
Isotype IgG1
Specificity This antibody reacts with erythrocyte ubiquitin. It does not react with multi ubiquitin.
Purification Protein A agarose
Background Ubiquitin is a polypeptide of 76 amino acid residues, and widely distributed protein in eukaryotic cells. This protein is also highly conserved among eukaryotic cells. There are several reports showed that intracellular abnormal and short-lived proteins are degraded through an ubiquitin dependent proteolytic pathway. In the ubiquitin dependent pathway, a target protein is tagged with multi-ubiquitin molecules.
Alternate names: Polyubiquitin-B, UBB
Gene ID 7314
UniProt P0CG47
Research Area Neurology, Proteolysis / Ubiquitin, Alzheimer's Disease, Proteases, Amino Acids
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS containing 50% glycerol, pH 7.2. No preservative is contained.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliqouts) at -20 °C.
Expiry Date 12 months
Supplier Images
anti-Ubiquitin antibody anti-Ubiquitin antibody
Background publications Miyazaki, Fujita, Ozaki et al.: "NEDL1, a novel ubiquitin-protein isopeptide ligase for dishevelled-1, targets mutant superoxide dismutase-1." in: The Journal of biological chemistry, Vol. 279, Issue 12, pp. 11327-35, 2004 (PubMed).

Uchida, Hatakeyama, Matsushima et al.: "AIRE functions as an E3 ubiquitin ligase." in: The Journal of experimental medicine, Vol. 199, Issue 2, pp. 167-72, 2004 (PubMed).

Zhang, Tomida, Koshimizu et al.: "Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex." in: Cancer research, Vol. 64, Issue 3, pp. 1114-21, 2004 (PubMed).

Akiyoshi, Hatakeyama, Pitkänen et al.: "Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner." in: The Journal of biological chemistry, Vol. 279, Issue 32, pp. 33984-91, 2004 (PubMed).

Hatakeyama, Matsumoto, Yada et al.: "Interaction of U-box-type ubiquitin-protein ligases (E3s) with molecular chaperones." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 9, Issue 6, pp. 533-48, 2004 (PubMed).

Okumura, Hatakeyama, Matsumoto et al.: "Functional regulation of FEZ1 by the U-box-type ubiquitin ligase E4B contributes to neuritogenesis." in: The Journal of biological chemistry, Vol. 279, Issue 51, pp. 53533-43, 2004 (PubMed).

Komatsu, Waguri, Ueno et al.: "Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice." in: The Journal of cell biology, Vol. 169, Issue 3, pp. 425-34, 2005 (PubMed).

Tanji, Tanaka, Mori et al.: "NUB1 suppresses the formation of Lewy body-like inclusions by proteasomal degradation of synphilin-1." in: The American journal of pathology, Vol. 169, Issue 2, pp. 553-65, 2006 (PubMed).

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