Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Glypican 3 antibody (Middle Region)

GPC3 Reactivity: Human IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449428
  • Target See all Glypican 3 (GPC3) Antibodies
    Glypican 3 (GPC3)
    Binding Specificity
    • 20
    • 16
    • 13
    • 12
    • 7
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 345-370, Middle Region
    Reactivity
    • 153
    • 48
    • 48
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 97
    • 55
    • 2
    Rabbit
    Clonality
    • 82
    • 71
    • 1
    Polyclonal
    Conjugate
    • 64
    • 13
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glypican 3 antibody is un-conjugated
    Application
    • 83
    • 82
    • 71
    • 51
    • 41
    • 26
    • 18
    • 17
    • 6
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human and Mouse Glypican 3 (GPC3). Other species not tested.
    Purification
    Protein G Column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide selected from the center region of Human GPC3 (aa 345-370)
    Isotype
    Ig Fraction
    Top Product
    Discover our top product GPC3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    Glypican 3 (GPC3)
    Alternative Name
    Glypican-3 / GPC3 (GPC3 Products)
    Synonyms
    GPC3 antibody, sgb antibody, dgsx antibody, sdys antibody, sgbs antibody, oci-5 antibody, sgbs1 antibody, DGSX antibody, GTR2-2 antibody, MXR7 antibody, OCI-5 antibody, SDYS antibody, SGB antibody, SGBS antibody, SGBS1 antibody, Glypican-3 antibody, glypican 3 antibody, gpc3 antibody, GPC3 antibody, Gpc3 antibody
    Background
    GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.Synonyms: GTR2-2, Intestinal protein OCI-5, MXR7, OCI5
    Gene ID
    2719, 9606
    UniProt
    P51654
    Pathways
    Glycosaminoglycan Metabolic Process
You are here:
Support