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ATG4B antibody (N-Term)

ATG4B Reactivity: Human, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1449637
  • Target See all ATG4B Antibodies
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Binding Specificity
    • 21
    • 17
    • 15
    • 13
    • 13
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-53, N-Term
    Reactivity
    • 117
    • 44
    • 28
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 115
    • 4
    Rabbit
    Clonality
    • 113
    • 6
    Polyclonal
    Conjugate
    • 52
    • 10
    • 9
    • 9
    • 7
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ATG4B antibody is un-conjugated
    Application
    • 99
    • 41
    • 27
    • 27
    • 23
    • 15
    • 13
    • 13
    • 11
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Purification
    Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
    Immunogen
    KLH conjugated synthetic peptide between 23~53 amino acids from the N-terminal region of Human APG4B Genename: ATG4B
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ATG4B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    ATG4B (Autophagy related 4B Cysteine Peptidase (ATG4B))
    Alternative Name
    APG4B / ATG4B (ATG4B Products)
    Synonyms
    apg4b antibody, APG4B antibody, AUTL1 antibody, 2510009N07Rik antibody, AW048066 antibody, Apg4b antibody, Atg4bl antibody, Autl1 antibody, Aut2b2 antibody, autophagy related 4B cysteine peptidase antibody, autophagy-related 4b antibody, Peptidase family C54 protein antibody, cysteine protease ATG4B antibody, ATG4 autophagy related 4 homolog B (S. cerevisiae) antibody, autophagy related 4B, cysteine peptidase antibody, autophagy related 4B, cysteine peptidase L homeolog antibody, ATG4B antibody, Atg4b antibody, AT3G59950 antibody, Tsp_08582 antibody, Tsp_11599 antibody, atg4b antibody, atg4b.L antibody
    Background
    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG4 is a cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.Synonyms: AUT-like 1 cysteine endopeptidase, AUTL1, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, Cysteine protease ATG4B, KIAA0943
    Molecular Weight
    44309 Da
    Gene ID
    23192
    NCBI Accession
    NP_037457
    Pathways
    Autophagy
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