AFF2 antibody (N-Term)

Catalog No. ABIN1449858

Product Details anti-AFF2 Antibody

Target: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AFF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDLFDFFRDW DLEQQCHYEQ DRSALKKREW ERRNQEVQQE DDLFSSGFDL

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Horse, Rabbit, Guinea PigSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the N terminal of human AFF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for AFF2

Target: AFF2 (AF4/FMR2 Family, Member 2 (AFF2))

Alternative Name: AFF2 / FMR2 (AFF2 Products)

Synonyms: FMR2 antibody, FMR2P antibody, FRAXE antibody, MRX2 antibody, OX19 antibody, Fmr2 antibody, Ox19 antibody, Oxh antibody, AF4/FMR2 family member 2 antibody, AF4/FMR2 family, member 2 antibody, AFF2 antibody, Aff2 antibody

Background: AFF2 is a RNA-binding protein and might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure. Defects in AFF2 are the cause of mental retardation X-linked associated with fragile site FRAXE (MRFRAXE). A form of mild to moderate mental retardation associated with learning difficulties, communication deficits, attention problems, hyperactivity, and autistic behavior. It is associated with a fragile site on chromosome Xq28.Synonyms: AF4/FMR2 family member 2, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, Protein Ox19

Gene ID: 2334

NCBI Accession: NP_002016