ANG antibody (Middle Region)

Catalog No. ABIN1450000

Product Details anti-ANG Antibody

Target: ANG (Angiogenin (ANG))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANG antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: ANG antibody was raised against a 15 amino acid synthetic peptide near the center of human ANG.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for ANG

Target: ANG (Angiogenin (ANG))

Alternative Name: Angiogenin (ANG Products)

Synonyms: ALS9 antibody, HEL168 antibody, RNASE4 antibody, RNASE5 antibody, ANG antibody, AI385586 antibody, Ang1 antibody, Rnase5 antibody, Rnase5a antibody, ANG1 antibody, angiogenin antibody, angiogenin, ribonuclease, RNase A family, 5 antibody, ribonuclease A family member k6 antibody, ANG antibody, Ang antibody, RNASE6 antibody

Background: Angiogenin (ANG or ANG I) is important for the process of neovascularization and formation of new blood vessels. ANG is similar to pancreatic ribonuclease A and functions as a tRNA-specific ribonuclease that abolishes protein synthesis by specifically hydrolyzing cellular tRNAs. It interacts with endothelial cell-surface actin and may cause changes in the cell cytoskeleton. ANG is thought to be involved in the development of solid tumors and its antagonists are capable of inhibiting tumor growth. Defects in ANG are the cause of susceptibility to amyotrophic lateral sclerosis type 9 (ALS9). Angiogenin is a genetic link between ALS and PD.Synonyms: ANG, RNASE5, Ribonuclease 5

Molecular Weight: 16 kDa

Gene ID: 283

NCBI Accession: NP_001136