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TCTE3 antibody (T-Complex-Associated-Testis-Expressed 3) (N-Term)

Details for Product anti-TCTE3 Antibody No. ABIN1450006, Supplier: Log in to see
  • D17Leh117c
  • LC2
  • Tcte-3
  • Tctex-2
  • Tctex-4
  • TCTEX1D3
  • Tctex2
  • Tctex4
Human, Mouse (Murine), Rat (Rattus)
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
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Immunogen 19 amino acid synthetic peptide near the amino terminus of Human TCTEX1D3
Isotype IgG
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat.
Purification Affinity chromatography purified via peptide column
Alternative Name TCTE3
Background Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D3, also called TCTE3, has been identified as a gene responsible for congenital diaphragmatic hernia (CDH).Synonyms: T-complex testis-specific protein 3, T-complex-associated testis-expressed protein 3, TCTEX1D3, Tcte-3, Tctex1 domain-containing protein 3
Molecular Weight 22 kDa
Gene ID 6991
NCBI Accession NP_777570
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-TCTE3 antibody (T-Complex-Associated-Testis-Expressed 3) (N-Term) (ABIN1450006) Western blot analysis of TCTEX1D3 in EL4 cell lysate with TCTEX1D3 at 1 ug/mL in (A) ...
Background publications Teshiba, Masumoto, Esumi, Nagata, Kinoshita, Tajiri, Taguchi, Yamamoto: "Identification of TCTE3 as a gene responsible for congenital diaphragmatic hernia using a high-resolution single-nucleotide polymorphism array." in: Pediatric surgery international, Vol. 27, Issue 2, pp. 193-8, 2011

Li, Lee, Cooper: "NudEL targets dynein to microtubule ends through LIS1." in: Nature cell biology, Vol. 7, Issue 7, pp. 686-90, 2005

Chuang, Yeh, Bollati, Conde, Canavosio, Caceres, Sung: "The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth." in: Developmental cell, Vol. 9, Issue 1, pp. 75-86, 2005

He, Francis, Myers, Yu, Black, Baas: "Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 697-703, 2005

Watanabe, Fujiwara, Shimizu, Okuno, Suzuki, Takahashi, Nakamura, Hirai: "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q." in: Cytogenetics and cell genetics, Vol. 73, Issue 1-2, pp. 153-6, 1996