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Tctex1 Domain Containing 2 (TCTEX1D2) (N-Term) antibody

Details for Product No. ABIN1450007, Supplier: Log in to see
Antigen
  • RGD1563597
  • 0610012D17Rik
  • 2410011K15Rik
Epitope
N-Term
2
1
Reactivity
Human
4
Host
Rabbit
4
Clonality
Polyclonal
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
3
1
1
Supplier
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Immunogen 16 amino acid synthetic peptide near the amino terminus of Human TCTEX1D2
Isotype IgG
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography purified via peptide column
Alternative Name TCTEX1D2
Background Dyneins are multi-subunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. Cytoplasmic or axonemal Dynein is an approximately 12 subunit complex of two heavy chains, two intermediate chains to anchor Dynein to its cargo, four smaller intermediate chains and several light chains. It performs functions necessary for cell survival such as organelle transport and centrosome assembly. TCTEX1 is a cytoplasmic dynein light chain found in a complex with Na+ CP type X (SCN10A). TCTEX1D2, also called TCTEX1 domain containing 2, belongs to the dynein light chain TCTEX-type family. Its function is still under investigation.Synonyms: Tctex1 domain-containing protein 2
Molecular Weight 16 kDa
Gene ID 255758
NCBI Accession NP_689986
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS containing 0.02 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Tctex1 Domain Containing 2 (TCTEX1D2) (N-Term) antibody (ABIN1450007) Western blot analysis of TCTEX1D2 in K562 cell lysate with TCTEX1D2at 1 ug/mL in (A) ...
Background publications Pfister, Fisher, Gibbons et al.: "Cytoplasmic dynein nomenclature." in: The Journal of cell biology, Vol. 171, Issue 3, pp. 411-3, 2005 (PubMed).

Chuang, Yeh, Bollati et al.: "The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth." in: Developmental cell, Vol. 9, Issue 1, pp. 75-86, 2005 (PubMed).

Li, Lee, Cooper: "NudEL targets dynein to microtubule ends through LIS1." in: Nature cell biology, Vol. 7, Issue 7, pp. 686-90, 2005 (PubMed).

He, Francis, Myers et al.: "Role of cytoplasmic dynein in the axonal transport of microtubules and neurofilaments." in: The Journal of cell biology, Vol. 168, Issue 5, pp. 697-703, 2005 (PubMed).

Watanabe, Fujiwara, Shimizu et al.: "Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q." in: Cytogenetics and cell genetics, Vol. 73, Issue 1-2, pp. 153-6, 1996 (PubMed).