Transglutaminase 5 antibody (C-Term)

Catalog No. ABIN1450065

Product Details anti-Transglutaminase 5 Antibody

Target: Transglutaminase 5 (TGM5)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase 5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the carboxy terminus of Human TGM5

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Transglutaminase 5

Target: Transglutaminase 5 (TGM5)

Alternative Name: Transglutaminase-5 (TGM5) (TGM5 Products)

Synonyms: TGM5 antibody, TGASE5 antibody, TGASEX antibody, TGMX antibody, TGX antibody, 2310007C07Rik antibody, TGx antibody, transglutaminase 5 antibody, TGM5 antibody, tgm5 antibody, Tgm5 antibody

Background: Transglutaminases (TGM) are a family of structurally and functionally related Ca2+-dependent enzymes (TGases) that stabilize protein assemblies through the formation of gamma-glutamyl-epsilon lysine crosslinks. TGases influence numerous biological processes, including blood coagulation, cell differentiation, fertilization and apoptosis. TGM5 belongs to the transglutaminase superfamily and catalyzes the cross-linking of proteins between glutamine and lysine residues, often resulting in stabilization of protein assemblies. TGM5 is also expressed in the human hair follicle. Defects in TGM5 are associated with acral peeling skin syndrome.Synonyms: Protein-glutamine gamma-glutamyltransferase 5, TGMX, TGX, TGase 5, TGase X, Transglutaminase X

Gene ID: 9333

NCBI Accession: NP_963925