PRICKLE4 antibody (N-Term)

Catalog No. ABIN1450076

Product Details anti-PRICKLE4 Antibody

Target: PRICKLE4 (Prickle Homolog 4 (PRICKLE4))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRICKLE4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogen: 18 amino acid synthetic peptide near the amino terminus of Human PRICKLE4

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PRICKLE4

Target: PRICKLE4 (Prickle Homolog 4 (PRICKLE4))

Alternative Name: PRICKLE4 (PRICKLE4 Products)

Synonyms: C6orf49 antibody, OBTP antibody, OEBT antibody, TOMM6 antibody, prickle planar cell polarity protein 4 antibody, PRICKLE4 antibody

Background: PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.Synonyms: C6orf49, NRSF-interacting LIM domain protein 4, OBTP, OEBT, REST, TOMM6

Gene ID: 29964

NCBI Accession: NP_037529