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TLR8 antibody (C-Term)
TLR8
Reactivity: Human
IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TLR8 Antibody
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Target
See all TLR8 Antibodies
TLR8
(Toll-Like Receptor 8 (TLR8))
Binding Specificity
All epitopes for TLR8 antibodies
C-Term
Reactivity
All reactivities for TLR8 antibodies
Human
Host
All hosts for TLR8 antibodies
Rabbit
Clonality
All clonalities for TLR8 antibodies
Polyclonal
Conjugate
All conjugates for TLR8 antibodies
This TLR8 antibody is un-conjugated
Application
All applications for TLR8 antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Purification
Affinity chromatography purified via peptide column
Immunogen
15 amino acid synthetic peptide near the carboxy terminus of human TLR8
Isotype
IgG
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for TLR8
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Target
TLR8
(Toll-Like Receptor 8 (TLR8))
Alternative Name
CD288 / TLR8 (TLR8 Products )
Synonyms
CD288 antibody, toll like receptor 8 antibody, toll-like receptor 8 antibody, TLR8 antibody, Tlr8 antibody
Background
Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.Synonyms: Toll-like receptor 8, UNQ249/PRO286
Gene ID
51311
NCBI Accession
NP_619542
Pathways
TLR Signaling , Activation of Innate immune Response , Toll-Like Receptors Cascades
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