Cadherin (pan) antibody

Details for Product No. ABIN145920
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Antigen
Synonyms PCDH10, OLpcad, cadherin, ci-cadherin
Epitope
pan
(19), (6), (1), (1), (1)
Reactivity
Chicken
(27), (13), (8), (6), (5), (4), (3), (3), (3), (2), (2)
Host
Mouse
(24), (10)
Clonality
Monoclonal
Conjugate
Un-conjugated
(1)
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(22), (15), (6), (6), (4), (3), (3), (1)
Pubmed 7 references available
Catalog no. ABIN145920
Quantity 0.1 mL
Price
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Immunogen Synthetic peptide: DYDYLNDWGPRFKKLADMYGGGDD conjugated to KLH, corresponding to amino acids 889-912 of Chicken N-Cadherin (cdh2).
Isotype IgG1
Specificity Reacts with all cadherins. Cross Reactivity: Cross-reacts with Human, Mouse, Rat, Cat, Chicken, Cow, Dog, Goat, Guinea Pig, Hamster, Pig, Psammoys (sand rat), Rabbit, Sheep, Snake and Xenopus. Not yet tested in other species.
Cross-Reactivity Goat, Hamster, Human, Mouse (Murine), Rabbit, Rat (Rattus), Sheep (Ovine), Xenopus laevis
Purification Ascites
Background Mouse monoclonal [CH - 19] to pan Cadherin - Plasma Membrane Marker. Background: This product is useful for the detection of members of the cadherin family or genetically engineered proteins containing the C-terminal cadherin tail, and for demonstration of adherens type cell-cell junctions regardless of their cadherin type.
Research Area Extracellular Matrix, Signaling, Cytoskeleton
Application Notes IF: Use at a dilution of 1/500 using cultured MDBK cells. IHC-P: Use at a dilution of 1/500. Perform enzymatic antigen retrieval before commencing with IHC staining protocol (Formalin-fixed paraffin-embedded sections). WB: Use at an assay dependant dilution. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid with 0.1% sodium azide
Preservative Sodium azide
Storage 4 °C
Supplier Images
anti-Cadherin (pan) antibody anti-Cadherin (pan) antibody
General Takeichi: "Cadherin cell adhesion receptors as a morphogenetic regulator." in: Science (New York, N.Y.), Vol. 251, Issue 5000, pp. 1451-5, 1991 (PubMed).

Kartenbeck, Schmelz, Franke et al.: "Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium." in: The Journal of cell biology, Vol. 113, Issue 4, pp. 881-92, 1991 (PubMed).

Geiger, Volberg, Ginsberg et al.: "Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-cadherin." in: Journal of cell science, Vol. 97 ( Pt 4), pp. 607-14, 1991 (PubMed).

Takeichi: "Cadherins: a molecular family important in selective cell-cell adhesion." in: Annual review of biochemistry, Vol. 59, pp. 237-52, 1990 (PubMed).

Takeichi: "The cadherins: cell-cell adhesion molecules controlling animal morphogenesis." in: Development (Cambridge, England), Vol. 102, Issue 4, pp. 639-55, 1988 (PubMed).

Grunwald: "The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules." in: Current opinion in cell biology, Vol. 5, Issue 5, pp. 797-805, 1993 (PubMed).

Takeichi: "Cadherins in cancer: implications for invasion and metastasis." in: Current opinion in cell biology, Vol. 5, Issue 5, pp. 806-11, 1993 (PubMed).

Hosts (24), (10)
Reactivities (27), (13), (8), (6), (5), (4), (3), (3), (3), (2), (2)
Applications (22), (15), (6), (6), (4), (3), (3), (1)
Conjugates (1)
Epitopes (19), (6), (1), (1), (1)
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