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Drebrin-Like (DBNL) antibody

Details for Product No. ABIN147001
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Antigen
Synonyms wu:fb34f02, zgc:91835, dbnl, zgc:112450, DBNL, DKFZp459C0939, ABP1, HIP-55, HIP55, SH3P7, Abp1, mAbp1, Sh3p7, abp1, dbnl-B
Reactivity
Human
(36), (18), (16), (1)
Host
Goat
(32), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(26), (11), (10), (5), (5), (4), (2), (1)
Pubmed 2 references available
Quantity 50 µg
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Catalog No. ABIN147001
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Immunogen Synthetic peptide: AANLSRNGPALQE (Human).
Isotype IgG
Cross-Reactivity Mouse (Murine), Dog (Canine), Rat (Rattus)
Purification Immunogen affinity purified. Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide..
Alternative Name Drebrin-like protein (DBNL)
Background HIP55 possesses a SCAD domain that binds to polymerized actin and an SH3 domain. The latter is suggested to bind to Dynamin 1, a protein involved in the mechanism responsible for the formation of endocytotic vesicles.
Synonyms: HIP55, DBNL, SH3P7, Q9UJU6, 28988, HIP-55, HIP 55
Application Notes WB: Use at a concentration of 1-3 ug/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 49 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Comment

Positive Controls: Jurkat and 3T3 lysates.

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris-saline pH 7.3 containing 0.5% BSA and 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment Upon receipt - Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
anti-Drebrin-Like (DBNL) antibody anti-Drebrin-Like (DBNL) antibody
General Lefkowitz: "Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1651-8, 1976 (PubMed).

Ensenat, Yao, Wang et al.: "A novel src homology 3 domain-containing adaptor protein, HIP-55, that interacts with hematopoietic progenitor kinase 1." in: The Journal of biological chemistry, Vol. 274, Issue 48, pp. 33945-50, 1999 (PubMed).

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