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Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) antibody

Details for Product No. ABIN147445
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Antigen
Synonyms DD5, EDD, EDD1, HYD, 4432411E13Rik, AW549941, C77315, D030042K14, Edd, Edd1, mKIAA0896, Dd5, Rat100
Reactivity
Human
(54), (32), (17), (15), (12), (12), (3), (3)
Host
Goat
(44), (7), (1), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(34), (32), (21), (17), (10), (5), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Catalog No. ABIN147445
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide: LAIKTKNFGFV from C Terminus of the protein sequence according to NP_056986.
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Purified IgG fraction
Alternative Name UBR5 / HYD
Background This is a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22, a locus disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
Application Notes ELISA: peptide ELISA (antibody detection limit dilution >1 / 32000). WB: Approx. 35-40 kDa band observed in Human Testis, Human Muscle, A549 and A431 lysates at 0.5-1ug of primary. Please note that the band we observe is different from the predicted size of approx. 322 kDa according to NP_056986 (furthermore, our SDS PAGE/western blotting protocol is not optimized for detection of proteins as large as the predicted). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
General Callaghan, Russell, Woollatt et al.: "Identification of a human HECT family protein with homology to the Drosophila tumor suppressor gene hyperplastic discs." in: Oncogene, Vol. 17, Issue 26, pp. 3479-91, 1999 (PubMed).

Hosts (44), (7), (1), (1)
Reactivities (54), (32), (17), (15), (12), (12), (3), (3)
Applications (34), (32), (21), (17), (10), (5), (2), (1)
Conjugates (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (6), (4), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN147445
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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