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Fem-1 Homolog B (C. Elegans) (FEM1B) antibody

Details for Product No. ABIN147551
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Antigen
Reactivity
Human
(34), (26), (26), (13), (12), (2)
Host
Rabbit
(32), (2), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(24), (11), (9), (8), (7), (7), (1), (1), (1)
Pubmed 2 references available
Quantity 50 µg
Shipping to United States (Change)
Catalog No. ABIN147551
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Available on request
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Immunogen affinity purified
Alternative Name FEM1B
Background F1A alpha, also termed FEM1 beta, is a novel protein that associates with the intracellular domains of Fas and TNFR1. Over expression of F1A alpha induces apoptosis. F1A alpha also associates with CED-4 and its mammalian homologue Apaf-1, and can be cleaved by CED-3 and caspases.
Application Notes WB: Use at a concentration of 1-2 ug/ml. A 70kDa band is observed when using mouse liver tissue lysate. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml
Buffer PBS pH 7.2 with 50% glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
General Lefkowitz: "Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1651-8, 1976 (PubMed).

Chan, Tan, Zhang et al.: "F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis." in: The Journal of biological chemistry, Vol. 274, Issue 45, pp. 32461-8, 1999 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN147551
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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