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Details for Product No. ABIN147551

Fem-1 Homolog B (C. Elegans) (FEM1B) antibody

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Synonyms F1A-ALPHA, F1AA, FEM1-beta, mKIAA0396, FEM1B
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN147551
Quantity 50 µg
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Immunogen Available on request
Isotype IgG
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Purification Immunogen affinity purified
Alternative Name FEM1B
Background F1A alpha, also termed FEM1 beta, is a novel protein that associates with the intracellular domains of Fas and TNFR1. Over expression of F1A alpha induces apoptosis. F1A alpha also associates with CED-4 and its mammalian homologue Apaf-1, and can be cleaved by CED-3 and caspases.
Application Notes WB: Use at a concentration of 1-2 ug/ml. A 70kDa band is observed when using mouse liver tissue lysate. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/ml
Buffer PBS pH 7.2 with 50% glycerol
Preservative Sodium azide
Storage -20 °C
Lefkowitz: "Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1651-8, 1976 (PubMed).

Chan, Tan, Zhang et al.: "F1Aalpha, a death receptor-binding protein homologous to the Caenorhabditis elegans sex-determining protein, FEM-1, is a caspase substrate that mediates apoptosis." in: The Journal of biological chemistry, Vol. 274, Issue 45, pp. 32461-8, 1999 (PubMed).

Alternatives for antigen "Fem-1 Homolog B (C. Elegans) (FEM1B)", type "Antibodies"
Hosts (19), (3), (1)
Reactivities (20), (11), (11), (2), (2), (1)
Applications (23), (7), (4), (4), (1), (1)
Epitopes (8), (3), (1), (1), (1)