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Inhibitor of Growth Family, Member 2 (ING2) (C-Term) antibody

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Synonyms ING2, INGX, ING1L, p33ING2, 2810011M06Rik, Ing1l, Ing2b, P33ING2
(15), (14), (13), (11), (5), (3), (2), (2), (2), (1), (1), (1)
(69), (9), (9), (3), (1), (1), (1)
(37), (16), (16)
(3), (3), (3), (3), (3), (3)
Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(59), (43), (11), (5), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Peptide with sequence DKSTEKTKKDRRSR, from C Terminus of the protein sequence according to NP_001555
Isotype IgG
Purification IgG fraction. Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide..
Alternative Name ING2 / ING1L (ING2 Antibody Abstract)
Background This protein is similar to ING1, a tumor suppressor protein that can bind TP53, inhibit cell growth, and induce apoptosis. This protein binds phosphoinositides (PtdInPs) at its plant homeodomain (PHD) domain and it acts as a PtdInPs receptor. PtdInPs binding regulates the ability of this protein to activate TP53 and TP53-dependent apoptosis.
Synonyms: ING1L, p33ING2
Application Notes IF: Use at an assay dependent dilution. WB: Use at a concentration of 2-4 ug/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 32.8 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.

Positive Controls: HepG2 lysate

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment Upon receipt - Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
Western Blotting (WB) image for anti-Inhibitor of Growth Family, Member 2 (ING2) (C-Term) antibody (ABIN147814) anti-Inhibitor of Growth Family, Member 2 (ING2) (C-Term) antibody
Background publications Shimada, Saito, Suzuki et al.: "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor." in: Cytogenetics and cell genetics, Vol. 83, Issue 3-4, pp. 232-5, 1999 (PubMed).

Catalog No. ABIN147814
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