Inhibitor of Growth Family, Member 2 (ING2) antibody

Details for Product No. ABIN147814
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Antigen
Synonyms ING1L, p33ING2, Ing1l, Ing2b, P33ING2, 2810011M06Rik, ING2, INGX
Reactivity
Human
(30), (2), (2), (1)
Host
Goat
(18), (7), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(24), (15), (4), (4), (3), (2)
Pubmed 1 reference available
Catalog no. ABIN147814
Quantity 50 µg
Price
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence DKSTEKTKKDRRSR, from C Terminus of the protein sequence according to NP_001555
Isotype IgG
Purification Ig Fraction
Alternative Name ING2 / ING1L
Background This protein is similar to ING1, a tumor suppressor protein that can bind TP53, inhibit cell growth, and induce apoptosis. This protein binds phosphoinositides (PtdInPs) at its plant homeodomain (PHD) domain and it acts as a PtdInPs receptor. PtdInPs binding regulates the ability of this protein to activate TP53 and TP53-dependent apoptosis.
Application Notes IF: Use at an assay dependent dilution. WB: Use at a concentration of 2-4 ug/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 32.8 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
General Shimada, Saito, Suzuki et al.: "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor." in: Cytogenetics and cell genetics, Vol. 83, Issue 3-4, pp. 232-5, 1999 (PubMed).

Hosts (18), (7), (5)
Reactivities (30), (2), (2), (1)
Applications (24), (15), (4), (4), (3), (2)
Conjugates (1), (1), (1), (1), (1), (1)
Epitopes (7), (6), (3), (3), (2), (2), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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