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Details for Product No. ABIN147814

Inhibitor of Growth Family, Member 2 (ING2) antibody

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Antigen
Synonyms ING1L, p33ING2, Ing1l, Ing2b, P33ING2, 2810011M06Rik, ING2, INGX
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Application
»Alternatives Immunofluorescence (IF), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN147814
Quantity 50 µg
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Immunogen Peptide with sequence DKSTEKTKKDRRSR, from C Terminus of the protein sequence according to NP_001555
Isotype IgG
Purification Ig Fraction
Alternative Name ING2 / ING1L
Background This protein is similar to ING1, a tumor suppressor protein that can bind TP53, inhibit cell growth, and induce apoptosis. This protein binds phosphoinositides (PtdInPs) at its plant homeodomain (PHD) domain and it acts as a PtdInPs receptor. PtdInPs binding regulates the ability of this protein to activate TP53 and TP53-dependent apoptosis.
Application Notes IF: Use at an assay dependent dilution. WB: Use at a concentration of 2-4 ug/ml. Detects a band of approximately 33 kDa (predicted molecular weight: 32.8 kDa). Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Storage -20 °C
Shimada, Saito, Suzuki et al.: "Cloning of a novel gene (ING1L) homologous to ING1, a candidate tumor suppressor." in: Cytogenetics and cell genetics, Vol. 83, Issue 3-4, pp. 232-5, 1999 (PubMed).

Alternatives for antigen "Inhibitor of Growth Family, Member 2 (ING2)", type "Antibodies"
Hosts (10), (7), (6)
Reactivities (22), (2), (2), (1)
Applications (18), (9), (4), (3), (3), (2)
Epitopes (4), (3), (2), (1), (1), (1), (1)
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