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Details for Product No. ABIN148176

Ring Finger Protein 19A (RNF19A) antibody

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Synonyms RNF19, AA032313, Dorfin, Rnf19, UIP117, Ubce7ip2, XYbp, RNF19A
»Alternatives Human
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN148176
Quantity 0.1 mg
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Immunogen Peptide with sequence QTMELKVAIQTEI, from C Terminus of the protein sequence according to NP_056250.
Isotype IgG
Purification Purified IgG fraction
Alternative Name RNF19A / RNF19
Background The protein contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinsons disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Application Notes ELISA: peptide ELISA (antibody detection limit dilution 1/16000). Western Blot: No signal obtained yet but low background observed in Human Muscle, Human Kidney, Human Liver, Human Heart and Human Brain lysates at up to 2.0 ug/ml.
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Storage -20 °C
Gunther, Laithier, Brison: "A set of proteins interacting with transcription factor Sp1 identified in a two-hybrid screening." in: Molecular and cellular biochemistry, Vol. 210, Issue 1-2, pp. 131-42, 2000 (PubMed).

Alternatives for antigen "Ring Finger Protein 19A (RNF19A)", type "Antibodies"
Hosts (25), (5), (3)
Reactivities (32), (20), (14), (14), (14), (13)
Applications (21), (17), (10), (4), (3), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (2), (2), (2), (1), (1), (1)