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FOXP3 antibody (Forkhead Box P3) (AA 416-427)

Details for Product anti-FOXP3 Antibody No. ABIN148250, Supplier: Login to see
Antigen
  • foxp3
  • FOXP3
  • AIID
  • DIETER
  • IPEX
  • PIDX
  • XPID
  • JM2
  • scurfin
  • sf
  • RGD1562112
Epitope
AA 416-427
89
23
14
13
13
13
11
6
6
6
6
5
5
5
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Mouse (Murine)
328
183
57
22
22
21
16
12
9
8
2
2
1
1
Host
Goat
207
131
66
34
Clonality
Polyclonal
Conjugate
This FOXP3 antibody is un-conjugated
36
30
21
19
15
13
11
10
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
Application
ELISA, Western Blotting (WB)
243
166
145
88
38
33
30
29
19
17
16
6
5
5
2
2
2
1
1
Supplier
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Immunogen Synthetic peptide: KRSQRPNKCSNP, corresponding to amino acids 416-427 of Mouse FOXP3.
Isotype IgG
Specificity This antibody recognises a band at 50kd representing FOXP3 in HEK293 lysates overexpressing mouse FOXP3. However, the antibody also detects other similarly sized non-specific bands. This antibody will continue to be available until we can produce a more s
Cross-Reactivity Human, Dog (Canine), Monkey, Rat (Rattus)
Purification Affinity purified with antigen.
Alternative Name FOXP3 (FOXP3 Antibody Abstract)
Background FOXP3 (a 381 amino acid protein) is a member of the forkhead/winged-helix family of transcriptional regulators and is highly conserved across mammals. FOXP3 is essential for normal immune homeostasis.
Synonyms: 50943, sf, PIDX, Q9BZS1, Foxp3, AIID, scurfin, JM2, DIETER, 20371, 222100, XPID, IPEX
Research Area Immunology, Adaptive Immunity, Transcription Factors
Pathways
Application Notes Western Blot: use at 1/500. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris-saline containing 0.5% BSA and 0.02% sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment Upon Receipt - Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
 image for anti-FOXP3 antibody (Forkhead Box P3) (AA 416-427) (ABIN148250) anti-Forkhead Box P3 (FOXP3) (AA 416-427) antibody
Background publications Zenclussen, Gerlof, Zenclussen et al.: "Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model." in: The American journal of pathology, Vol. 166, Issue 3, pp. 811-22, 2005 (PubMed).