Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 9-31) antibody

Details for Product No. ABIN148292
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Synonyms zgc:91924, CCR10, AI464239, CCR9, Ccbp2, Cmkbr9, D6, GPR2, Gpr2
AA 9-31
(20), (16), (9), (5), (5), (4), (2), (1), (1), (1), (1)
(69), (18), (2), (1), (1)
(56), (17), (5), (2)
(6), (4), (2), (2), (2), (2)
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(53), (34), (26), (25), (17), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Immunogen Synthetic peptide: VSWGHYSGDEEDAYSAEPLPELC, corresponding to amino acids 9-31 of Human CCR10.
Isotype IgG
Specificity Peptide sequence is < 50 % identical to other human chemokine receptors in this region.
Characteristics Cellular Localization: Cell Membrane
Purification Immunogen affinity purified.
Alternative Name CCR10 / GPR2 (CCR10 Antibody Abstract)
Background Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 that displays chemotactic activity for resting CD4+ and CD8+ T cells.
Synonyms: 2826, 600240, GPR2, P46092, CCR10
Research Area Chemokines, Receptors
Application Notes ELISA: Use at a dilution of 1/75000. ICC: Use at a dilution of 1/1000. IHC-P: Use at a dilution of 1/500. WB: Use at a dilution of 1/250. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer 10 mM KHPO4, 140 mM NaCl, pH 7.2 with 1 mg/ml BSA and 0.1 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot and store at -20 to -80 °C
Supplier Images
Immunohistochemistry (IHC) image for anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 9-31) antibody (ABIN148292) anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (AA 9-31) antibody
Background publications Zaballos, Gutiérrez, Varona et al.: "Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 10, pp. 5671-5, 1999 (PubMed).

Lefkowitz: "Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1651-8, 1976 (PubMed).

Catalog No. ABIN148292
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