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Details for Product No. ABIN148292

Chemokine (C-C Motif) Receptor 10 (CCR10) antibody

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Antigen
Synonyms GPR2, Cmkbr9, Gpr2, zgc:91924, si:ch211-240b21.3, CCR10
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), ELISA
Pubmed 2 references available
Catalog no. ABIN148292
Quantity 0.1 mg
Price
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Immunogen Synthetic peptide: VSWGHYSGDEEDAYSAEPLPELC, corresponding to amino acids 9-31 of Human CCR10.
Isotype IgG
Specificity Peptide sequence is < 50 % identical to other human chemokine receptors in this region.
Purification Immunogen affinity purified
Alternative Name CCR10 / GPR2
Background Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 that displays chemotactic activity for resting CD4+ and CD8+ T cells.
Research Area Chemokines, Receptors
Application Notes ELISA: Use at a dilution of 1/75000. ICC: Use at a dilution of 1/1000. IHC-P: Use at a dilution of 1/500. WB: Use at a dilution of 1/250. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Concentration 2 mg/ml
Buffer 10 mM KHPO4, 140 mM NaCl, pH 7.2 with 1 mg/ml BSA and 0.1 % sodium azide.
Preservative Sodium azide
Storage -20 °C
Lefkowitz: "Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1651-8, 1976 (PubMed).

Zaballos, Gutiuerrez, Varona et al.: "Cutting edge: identification of the orphan chemokine receptor GPR-9-6 as CCR9, the receptor for the chemokine TECK." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 10, pp. 5671-5, 1999 (PubMed).

Alternatives for antigen "Chemokine (C-C Motif) Receptor 10 (CCR10)", type "Antibodies"
Hosts (54), (8), (1)
Reactivities (55), (28), (18), (17), (17), (17), (1), (1), (1)
Applications (31), (30), (28), (15), (10), (2), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (6), (4), (3), (2), (2), (1), (1), (1), (1)
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