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ALMS1 antibody (Alstrom Syndrome 1) (C-Term)

Details for Product anti-ALMS1 Antibody No. ABIN148489, Supplier: Login to see
Antigen
  • ALMS1
  • ALSS
  • bbb
Epitope
C-Term
17
5
2
1
1
1
Reactivity
Human
33
4
3
3
3
1
1
1
Host
Goat
18
16
Clonality
Polyclonal
Conjugate
This ALMS1 antibody is un-conjugated
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
21
20
16
2
2
2
2
1
1
Supplier
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Immunogen Synthetic peptide: RVTNQLLGRKVPWD from C Terminus of the protein sequence according to NP_055935.
Isotype IgG
Specificity The C terminus of ALMS 1 shares an 8 amino acid stretch with two other human proteins: hypothetical protein (XP_169104) and ERAL1 (NP_005693). However, this stretch is located internally in these two proteins and so will most likely not cross-react with this antibody. The N terminus was not chosen as the peptide is expected to cyclise during synthesis.
Cross-Reactivity Mouse (Murine)
Purification IgG fraction. Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide..
Alternative Name ALMS1 (ALMS1 Antibody Abstract)
Background This protein contains a large tandem-repeat domain that contains no cysteine residues. Mutations in this gene have been associated with Alstrom syndrome. The encoded protein may play a role in hearing, sight, obesity, and liver function. Alternative splice variants have been described but their full length sequences have not been determined.
Synonyms: 203800, KIAA0328, ALSS, ALMS1, Q8TCU4, 7840, DKFZp686A118, DKFZp686D1828
Research Area Immunology
Pathways
Application Notes ELISA: 1/3200. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment Upon receipt - Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
Immunohistochemistry (IHC) image for anti-ALMS1 antibody (Alstrom Syndrome 1) (C-Term) (ABIN148489) anti-Alstrom Syndrome 1 (ALMS1) (C-Term) antibody
Background publications Collin, Marshall, Ikeda et al.: "Mutations in ALMS1 cause obesity, type 2 diabetes and neurosensory degeneration in Alström syndrome." in: Nature genetics, Vol. 31, Issue 1, pp. 74-8, 2002 (PubMed).