Transient Receptor Potential Cation Channel, Subfamily M, Member 7 (TRPM7) antibody

Details for Product No. ABIN148580
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Antigen
Synonyms cb495, TRPM7, chak, chak1, ltrpc7, trp-plik, ALSPDC, CHAK, CHAK1, LTRPC7, TRP-PLIK, 2310022G15Rik, 4833414K03Rik, 5033407O22Rik, LTrpC-7, Ltpr7, Ltrpc7, TRPPLIK, Chak, Trp-plik
Reactivity
Human
(63), (56), (36), (19), (19), (17), (17), (3), (2)
Host
Goat
(62), (26), (8), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(75), (34), (29), (29), (24), (21), (18), (14), (2), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN148580
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Immunogen C-TKESESTNSVRLML
Isotype IgG
Specificity This antibody is specific for TRPM7 / LTRPC7.
Cross-Reactivity Mouse (Murine), Rat (Rattus), Crayfish
Characteristics Cellular Localization: Cell Membrane
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide..
Alternative Name TRPM7
Background The TRPM7 (Transient Receptor Protein-PhosphoLipase C-Interacting Kinase) protein is a member of the ion channel proteins. It regulates the calcium concentration in cells, which is imperative for such functions as muscle contractions and neuronal firing. TRPM7, however, is unique among the TRP channel proteins because it is bi-functional. It not only controls ion channels but it also acts as a kinase, phosphorylating proteins.
Synonyms: FLJ25718, TRPPLIK, TRP-PLIK, TRPM7 / LTRPC7, homolog of mouse transient receptor potentialphospholipase Cinteracting kinase CHaK hypothetical p, TRP PLIK
Research Area Neurology
Application Notes Western Blot-Approx 160-170kDa band seen in Daudi cell lysate. Recommended for use at 2.0-4.0ug/ml.
Comment

Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX20729-PEP).

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Minimize freezing and thawing.
Storage -20 °C
Storage Comment Aliquot and store at -20°C.
General Nadler, Hermosura, Inabe et al.: "LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability." in: Nature, Vol. 411, Issue 6837, pp. 590-5, 2001 (PubMed).

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