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Interferon Regulatory Factor 5 (IRF5) (C-Term) antibody

Details for Product No. ABIN148742, Supplier: Login to see
Antigen
  • IRF5
  • irf5
  • SLEB10
  • AW491843
  • mirf5
  • im:7155364
  • zgc:76986
Alternatives
anti-Human Interferon Regulatory Factor 5 antibody for Enzyme Immunoassay
Epitope
C-Term
21
12
8
4
4
4
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
104
35
24
9
4
4
2
2
2
1
1
1
Host
Goat
57
39
17
2
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
100
52
28
18
18
13
7
6
6
5
2
2
2
1
Supplier
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Immunogen Peptide with sequence QGPWPMHPAGMQ, from C Terminus of the protein sequence according to NP_002191, NP_116032
Isotype IgG
Specificity This antibody is expected to recognise both human isoforms.
Purification IgG fraction. Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide..
Alternative Name IRF5 (IRF5 Antibody Abstract)
Background This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative splice variants encoding different isoforms exist. [provided by RefSeq]
Synonyms: SLEB10
Research Area Chromatin and Nuclear Signaling, Transcription Factors, Innate Immunity, Cytokines
Pathways TLR Signaling
Application Notes Western Blot-Approx 55-60kDa band seen in A549 lysate (predicted MW 58 kDa). Recommended for use at 1.0-3.0ug/ml.
Comment

Positive Controls: A549 lysate

Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02% Na azide, pH7.3 with 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles.
Storage -20 °C
Storage Comment Upon receipt - Keep as concentrated solution. Aliquot and store at -20°C or below.
Supplier Images
Western Blotting (WB) image for anti-Interferon Regulatory Factor 5 (IRF5) (C-Term) antibody (ABIN148742) anti-Interferon Regulatory Factor 5 (IRF5) (C-Term) antibody
Western Blotting (WB) image for anti-Interferon Regulatory Factor 5 (IRF5) (C-Term) antibody (ABIN148742) anti-Interferon Regulatory Factor 5 (IRF5) (C-Term) antibody (Image 2)
Background publications Barnes, Moore, Pitha: "Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 23382-90, 2001 (PubMed).

Lefkowitz: "Identification of adenylate cyclase-coupled beta-adrenergic receptors with radiolabeled beta-adrenergic antagonists." in: Biochemical pharmacology, Vol. 24, Issue 18, pp. 1651-8, 1976 (PubMed).