CHRNB2 antibody (AA 351-362)

Catalog No. ABIN1493868

Product Details anti-CHRNB2 Antibody

Target: CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))

Binding Specificity: AA 351-362

Reactivity: Human, Bat, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This CHRNB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human CHRNB2.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Bat (100%) Mouse, Rat, Hamster, Bovine, Dog, Pig, Opossum (92%) Ferret, Xenopus (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide QPRHHCARQRLR from an internal region of human CHRNB2 (NP_000739.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Bat (100%), Mouse, Rat, Hamster, Bovine, Dog, Pig, Opossum (92%), Ferret, Xenopus (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:64000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx. 48 kDa band observed in Human Brain (Cerebellum, Cerebral Cortex) lysates (calculated MW of 57.0 kDa according to NP_000739.1). The observed molecular weight corresponds to earlier findings with different antibodies from other commercial sources. Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CHRNB2

Target: CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))

Alternative Name: CHRNB2 (CHRNB2 Products)

Synonyms: EFNL3 antibody, nAChRB2 antibody, NACHRB2 antibody, Acrb-2 antibody, Acrb2 antibody, C030030P04Rik antibody, [b]2-nAchR antibody, cholinergic receptor nicotinic beta 2 subunit antibody, cholinergic receptor nicotinic beta 2 subunit S homeolog antibody, cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) antibody, CHRNB2 antibody, chrnb2.S antibody, Chrnb2 antibody

Background: Name/Gene ID: CHRNB2
Subfamily: Nicotinic acetylcholine receptor
Family: Ion Channel

Synonyms: CHRNB2, AChR-beta1, Acrb2, EFNL3, NAChR beta 2, NAChRB2

Gene ID: 1141

NCBI Accession: NP_000739

UniProt: P17787

Pathways: Sensory Perception of Sound, Feeding Behaviour