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Details for Product No. ABIN151069

Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) antibody

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Synonyms ASD8, MRG-1, MRG1, P35SRJ, VSD2, Mrg1, Msg2, p35srj, AI835299, ER154-like, mrg1, zgc:103418, CITED2, cite2
»Alternatives Human
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
»Alternatives Western Blotting (WB)
Pubmed 7 references available
Catalog no. ABIN151069
Quantity 0.1 mL
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Immunogen Human CITED 2 protein.
Clone JA22
Isotype IgG1
Specificity This antibody is specific for CITED 2. Species Reactivity: Human. Does not work well on mouse. Other species have not been tested. Localization: Nuclear.
Cross-Reactivity Human, Mouse (Murine)
Purification Ascites
Alternative Name CITED2
Background Cited 2 is a cAMP-responsive element-binding protein (CBP)/p300 interactingtranscriptional modulator and a proposed negative regulator for hypoxia-induciblefactor-1 alpha. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptionalresponse to hypoxia. Alternate Names: anti-CITED2 antibody, anti-Cbp/p300-interacting transactivator antibody, anti-withGlu/Asp-rich carboxy-terminal domain antibody, anti-2antibody, anti-HGNC:1987antibody, anti-MRG1 antibody, anti-P35SRJ antibody, anti-CITED 2 antibody.
Gene ID 10370
UniProt Q99967
Research Area Cancer
Application Notes Suggested working dilutions: Western Blot 1:500
Restrictions For Research Use only
Format Liquid
Concentration 22.4 mg/ml
Buffer Preservative: Sodium Azide.
Preservative Sodium azide
Storage -20 °C
Bhattacharya, Michels, Leung et al.: "Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1." in: Genes & development, Vol. 13, Issue 1, pp. 64-75, 1999 (PubMed).

Leung, Jones, Michels et al.: "Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1." in: Genomics, Vol. 61, Issue 3, pp. 307-13, 2000 (PubMed).

Yin, Haynie, Yang et al.: "The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 16, pp. 10488-93, 2002 (PubMed).

Tien, Davis, Vanden Heuvel: "Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24053-63, 2004 (PubMed).

Bamforth, Braganuca, Farthing et al.: "Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway." in: Nature genetics, Vol. 36, Issue 11, pp. 1189-96, 2004 (PubMed).

Haase, Schott, Bornstein et al.: "CITED2 is expressed in human adrenocortical cells and regulated by basic fibroblast growth factor." in: The Journal of endocrinology, Vol. 192, Issue 2, pp. 459-65, 2007 (PubMed).

Dabir, Marinic, Krukovets et al.: "Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells." in: Circulation research, Vol. 102, Issue 12, pp. 1558-65, 2008 (PubMed).

Alternatives for antigen "Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2)", type "Antibodies"
Hosts (16), (8), (7), (1)
Reactivities (29), (15), (10), (3), (2), (1), (1), (1)
Applications (26), (17), (7), (1), (1), (1)
Epitopes (8), (7), (3), (2), (2), (1)