Cbp/p300-Interacting Transactivator, with Glu/Asp-Rich Carboxy-terminal Domain, 2 (CITED2) antibody

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Synonyms ASD8, MRG-1, MRG1, P35SRJ, VSD2, Mrg1, Msg2, p35srj, AI835299, ER154-like, mrg1, zgc:103418, CITED2, cite2
(24), (14), (10), (3), (2), (1), (1), (1)
(16), (6), (5), (1)
Clonality (Clone)
Monoclonal ()
Western Blotting (WB)
(24), (12), (7), (1), (1), (1)
Pubmed 7 references available
Catalog no. ABIN151069
Quantity 0.1 mL
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Immunogen Human CITED 2 protein.
Clone JA22
Isotype IgG1
Specificity This antibody is specific for CITED 2. Species Reactivity: Human. Does not work well on mouse. Other species have not been tested. Localization: Nuclear.
Cross-Reactivity Human, Mouse (Murine)
Purification Ascites
Alternative Name CITED2
Background Cited 2 is a cAMP-responsive element-binding protein (CBP)/p300 interactingtranscriptional modulator and a proposed negative regulator for hypoxia-induciblefactor-1 alpha. Recruitment of CBP/p300 by HIF-1 is essential for the transcriptionalresponse to hypoxia. Alternate Names: anti-CITED2 antibody, anti-Cbp/p300-interacting transactivator antibody, anti-withGlu/Asp-rich carboxy-terminal domain antibody, anti-2antibody, anti-HGNC:1987antibody, anti-MRG1 antibody, anti-P35SRJ antibody, anti-CITED 2 antibody.
Gene ID 10370
UniProt Q99967
Research Area Cancer
Application Notes Suggested working dilutions: Western Blot 1:500
Restrictions For Research Use only
Format Liquid
Concentration 22.4 mg/ml
Buffer Preservative: Sodium Azide.
Preservative Sodium azide
Storage -20 °C
General Bhattacharya, Michels, Leung et al.: "Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1." in: Genes & development, Vol. 13, Issue 1, pp. 64-75, 1999 (PubMed).

Leung, Jones, Michels et al.: "Molecular cloning and chromosomal localization of the human CITED2 gene encoding p35srj/Mrg1." in: Genomics, Vol. 61, Issue 3, pp. 307-13, 2000 (PubMed).

Yin, Haynie, Yang et al.: "The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 16, pp. 10488-93, 2002 (PubMed).

Tien, Davis, Vanden Heuvel: "Identification of the CREB-binding protein/p300-interacting protein CITED2 as a peroxisome proliferator-activated receptor alpha coregulator." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24053-63, 2004 (PubMed).

Bamforth, Braganuca, Farthing et al.: "Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway." in: Nature genetics, Vol. 36, Issue 11, pp. 1189-96, 2004 (PubMed).

Haase, Schott, Bornstein et al.: "CITED2 is expressed in human adrenocortical cells and regulated by basic fibroblast growth factor." in: The Journal of endocrinology, Vol. 192, Issue 2, pp. 459-65, 2007 (PubMed).

Dabir, Marinic, Krukovets et al.: "Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells." in: Circulation research, Vol. 102, Issue 12, pp. 1558-65, 2008 (PubMed).

Hosts (16), (6), (5), (1)
Reactivities (24), (14), (10), (3), (2), (1), (1), (1)
Applications (24), (12), (7), (1), (1), (1)
Epitopes (8), (6), (3), (2), (2), (1), (1)
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