You are viewing an incomplete version of our website. Please click to reload the website as full version.

Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) antibody

Details for Product No. ABIN151083, Supplier: Login to see
Antigen
  • FEN-1
  • FEN1
  • AW538437
  • MF1
  • RAD2
  • cb879
  • fen-1
  • fen1
  • mf1
  • rad2
  • xFEN1a
Alternatives
anti-Human Flap Structure-Specific Endonuclease 1 antibody for Immunoprecipitation
Epitope
AA 1-380
8
8
8
7
5
4
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
106
41
38
4
2
1
1
1
1
1
Host
Mouse
77
30
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
85
23
19
19
14
12
11
10
3
3
1
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Immunogen Recombinant human FEN-1 protein encoding amino acids 1-380 purified E. coli.
Clone 4E7
Isotype IgG1 kappa
Specificity This is specific for FEN-1.
Purification Protein G purified
Alternative Name FEN1 / RAD2 (FEN1 Antibody Abstract)
Background FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 kDa protein thatfunctions as an endonuclease that cleaves branched DNA structures containingsingle-stranded 5' flaps or as an exonuclease on DNA nicks and gaps. FEN-1endonuclease and exonuclease activities are stimulated by an association withproliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 is believed to haveimportant roles in DNA replication and repair and is required in cell-free DNA replicationsystems. Alternate Names: anti-Flap endonuclease 1 antibody, anti-flap structure specific endonuclease 1 antibody,anti-Maturation factor 1 antibody, anti-MF1 antibody, anti-RAD2 (S. pombe) homologantibody, anti- fen-1 antibody.
Gene Symbol: FEN1
Gene ID 2237
Pathways Telomere Maintenance, DNA Damage Repair
Application Notes Recommended dilutions: Flow Cytometry 1:10-1:1000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Western Blot 1-5 µg/mL
Restrictions For Research Use only
Buffer PBS [pH 7.4]
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
Background publications Qiu, Li, Frank et al.: "Cell cycle-dependent and DNA damage-inducible nuclear localization of FEN-1 nuclease is consistent with its dual functions in DNA replication and repair." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 4901-8, 2001 (PubMed).