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Ataxia Telangiectasia Mutated (ATM) (Ser1981), (AA 1974-1988) antibody

Details for Product No. ABIN151201
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Antigen
Epitope
Ser1981, AA 1974-1988
(53), (19), (12), (12), (9), (8), (5), (5), (5), (5), (5), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(227), (65), (38), (3), (2), (1), (1)
Host
Rabbit
(163), (41), (16), (7), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(7), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1)
Application
Western Blotting (WB), ELISA
(125), (50), (49), (48), (43), (40), (34), (12), (12), (5), (2), (2)
Pubmed 2 references available
Quantity 0.05 mg
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Catalog No. ABIN151201
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Immunogen Synthetic peptide: CSLAFEEGS/QSTTISS, corresponding to amino acids 1974-1988 of ATM, with a phosphorylation site at Ser1981
Specificity NB100-1679 is directed against human ATM kinase and can detect native and over-expressed proteins in various tissues and extracts.
Purification affinity purified
Alternative Name ATM
Background Alternate Names: anti-AT complementation group A antibody, anti-AT complementation group C antibody,anti-AT complementation group D antibody, anti-AT complementation group E antibody,anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxiatelangiectasia gene mutated antibody.
Gene Symbol: ATM
Gene ID 472
Application Notes Western blot: Molecular weight: 350 kDa.
Recommended dilutions: ELISA 1:10000 - 1:50000, Western Blot 1:500- 1:2000
Restrictions For Research Use only
Buffer 0.02 M Potassium Phosphate, 0.15 M sodium Chloride pH 7.2, Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Aliquot and store at -20 °C or -80 °C.
Supplier Images
anti-Ataxia Telangiectasia Mutated (ATM) (Ser1981), (AA 1974-1988) antibody anti-Ataxia Telangiectasia Mutated (ATM) (Ser1981), (AA 1974-1988) antibody
General Bakkenist, Kastan: "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation." in: Nature, Vol. 421, Issue 6922, pp. 499-506, 2003 (PubMed).

Chu, Yang, Lu et al.: "Silencing of p29 affects DNA damage responses with UV irradiation." in: Cancer research, Vol. 66, Issue 17, pp. 8484-91, 2006 (PubMed).

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