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Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody

Antigen

Ataxia Telangiectasia Mutated (ATM)
Synonyms AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, DKFZp781A0353, AI256621, C030026E19Rik, ATM, Tefu, atm/tefu, dATM, tef, DmelCG6535, CG6535, Xatm
Binding Site
Alternatives

pSer1981
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunofluorescence (IF), Western Blotting (WB)
2 references available
Catalog no. ABIN151201
Quantity 50 µg  (1.1 mg/ml)  (Variants)
Price Product not available in this region.
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anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody

Additional Information
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Alternative name ATM
Gene ID 472
Immunogen Synthetic peptide: CSLAFEEGSpQSTTISS, corresponding to amino acids1974-1988 of ATM.
Cross-Reactivity Human
Description Alternate Names: anti-AT complementation group A antibody, anti-AT complementation group C antibody,anti-AT complementation group D antibody, anti-AT complementation group E antibody,anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxiatelangiectasia gene mutated antibody.
Specificity ABIN151201 is directed against human ATM kinase and can detect native andover-expressed proteins in various tissues and extracts. Phosphorylated:Ser1981. Species Reactivity: Cross-reacts with Human. Not yet tested in other species. Localization: Nuclear. Also found in endocyticvesicles in association with beta adaptin.

Application Details
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Application Notes Suggested working dilutions: immunofluorescence 1/500,Western Blot 1/100-1/1000
Concentration 1.1 mg/ml
Purification Aff - Purified
Buffer 0.02 M Potassium phosphate, 0.15 M sodium Chloride pH 7.2. Preservative: 0.01% sodium azide.
Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Restrictions For Research Use only

Publications
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Bakkenist, Kastan: "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation." in: Nature, Vol. 421, Issue 6922, pp. 499-506, 2003 (PubMed).

Chu, Yang, Lu et al.: "Silencing of p29 affects DNA damage responses with UV irradiation." in: Cancer research, Vol. 66, Issue 17, pp. 8484-91, 2006 (PubMed).

Alternatives
Application Details Publications Images Variants back to top

Alternatives for antigen "Ataxia Telangiectasia Mutated (ATM)", type "Antibodies"
Hosts Rabbit (105), Mouse (31), Goat (8), Sheep (5), Chicken (2)
Reactivities Human (145), Mouse (Murine) (72), Rat (Rattus) (54), Hamster (2), Monkey (2)
Applications Western Blotting (WB) (69), Immunofluorescence (IF) (55), ELISA (30), Immunoprecipitation (IP) (30), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (26), Immunohistochemistry (IHC) (19), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (9), Immunocytochemistry (ICC) (8), Immunoelectron Microscopy (IEM) (3), Dot Blot (Dot) (2), Fluorescence Microscopy (FM) (2), Immunohistochemistry (Fixed) (IHC (fx)) (2), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (3), Alexa Fluor 488 (3), Alexa Fluor 555 (3), Alexa Fluor 647 (3), Biotin (3), Cy3 (3), Cy5 (3), Cy5.5 (3), Cy7 (3), FITC (3), Gold (3), HRP (3), PE (3), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
Epitopes pSer1981 (41), C-Term (20), pTyr170 (18), AA 1391-1693 (4), AA 2577-3056 (4), AA 1-308 (3), AA 1980-2338 (3), AA 980-1512 (3), Ser1981 (3), N-Term (2), AA 1248-1332 (1), AA 1653-2032 (1), AA 1750-1800 (1), AA 2050-2717 (1), AA 2550-2600 (1), AA 5055-6585 (1), Internal Region (1)