Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody

Details for Product No. ABIN151201
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Antigen
Synonyms AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, AI256621, C030026E19Rik, ATM, Atm, CG6535, Dmel\\CG6535, Tefu, atm, atm/tefu, dATM, tef, Xatm, at1, atdc, tel1, telo1
Epitope
pSer1981
(49), (15), (12), (12), (4), (4), (4), (4), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(205), (69), (39), (4), (4), (1), (1)
Host
Rabbit
(149), (47), (12), (6), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(130), (51), (46), (46), (40), (39), (32), (12), (7), (4), (3), (2)
Pubmed 2 references available
Catalog no. ABIN151201
Quantity 50 µg
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Immunogen Synthetic peptide: CSLAFEEGSpQSTTISS, corresponding to amino acids1974-1988 of ATM.
Specificity ABIN151201 is directed against human ATM kinase and can detect native andover-expressed proteins in various tissues and extracts. Phosphorylated:Ser1981. Species Reactivity: Cross-reacts with Human. Not yet tested in other species. Localization: Nuclear. Also found in endocyticvesicles in association with beta adaptin.
Cross-Reactivity Human
Purification Aff - Purified
Alternative Name ATM
Background Alternate Names: anti-AT complementation group A antibody, anti-AT complementation group C antibody,anti-AT complementation group D antibody, anti-AT complementation group E antibody,anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxiatelangiectasia gene mutated antibody.
Gene ID 472
Application Notes Suggested working dilutions: immunofluorescence 1/500,Western Blot 1/100-1/1000
Restrictions For Research Use only
Concentration 1.1 mg/ml
Buffer 0.02 M Potassium phosphate, 0.15 M sodium Chloride pH 7.2. Preservative: 0.01% sodium azide.
Preservative Sodium azide
Storage -20 °C
Supplier Images
anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody anti-Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody
General Bakkenist, Kastan: "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation." in: Nature, Vol. 421, Issue 6922, pp. 499-506, 2003 (PubMed).

Chu, Yang, Lu et al.: "Silencing of p29 affects DNA damage responses with UV irradiation." in: Cancer research, Vol. 66, Issue 17, pp. 8484-91, 2006 (PubMed).

Hosts (149), (47), (12), (6), (3)
Reactivities (205), (69), (39), (4), (4), (1), (1)
Applications (130), (51), (46), (46), (40), (39), (32), (12), (7), (4), (3), (2)
Conjugates (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (1), (1), (1)
Epitopes (49), (15), (12), (12), (4), (4), (4), (4), (4), (4), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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