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Details for Product No. ABIN151201

Ataxia Telangiectasia Mutated (ATM) (pSer1981) antibody

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Antigen
Synonyms AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1, AI256621, C030026E19Rik, ATM, Atm, CG6535, Dmel\\CG6535, Tefu, atm, atm/tefu, dATM, tef, Xatm, at1, atdc, tel1, telo1
Epitope
»Alternatives pSer1981
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunofluorescence (IF), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN151201
Quantity 50 µg
Price
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Immunogen Synthetic peptide: CSLAFEEGSpQSTTISS, corresponding to amino acids1974-1988 of ATM.
Specificity ABIN151201 is directed against human ATM kinase and can detect native andover-expressed proteins in various tissues and extracts. Phosphorylated:Ser1981. Species Reactivity: Cross-reacts with Human. Not yet tested in other species. Localization: Nuclear. Also found in endocyticvesicles in association with beta adaptin.
Cross-Reactivity Human
Purification Aff - Purified
Alternative Name ATM
Background Alternate Names: anti-AT complementation group A antibody, anti-AT complementation group C antibody,anti-AT complementation group D antibody, anti-AT complementation group E antibody,anti-AT mutated protein antibody, anti-AT1 antibody, anti-ATA antibody, anti-Ataxiatelangiectasia gene mutated antibody.
Gene ID 472
Application Notes Suggested working dilutions: immunofluorescence 1/500,Western Blot 1/100-1/1000
Restrictions For Research Use only
Concentration 1.1 mg/ml
Buffer 0.02 M Potassium phosphate, 0.15 M sodium Chloride pH 7.2. Preservative: 0.01% sodium azide.
Preservative Sodium azide
Storage -20 °C
Bakkenist, Kastan: "DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation." in: Nature, Vol. 421, Issue 6922, pp. 499-506, 2003 (PubMed).

Chu, Yang, Lu et al.: "Silencing of p29 affects DNA damage responses with UV irradiation." in: Cancer research, Vol. 66, Issue 17, pp. 8484-91, 2006 (PubMed).

Alternatives for antigen "Ataxia Telangiectasia Mutated (ATM)", type "Antibodies"
Hosts (153), (59), (18), (6), (4)
Reactivities (229), (74), (44), (5), (4), (1), (1)
Applications (142), (69), (54), (48), (42), (40), (34), (13), (10), (7), (3), (2), (2)
Conjugates (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (1), (1)
Epitopes (52), (15), (12), (12), (4), (4), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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